5 Result(s)
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Article
Open AccessThe role of disconnection in explaining disability in multiple sclerosis
In multiple sclerosis, the correlation between white matter lesion volumes (LV) and expanded disability status scale (EDSS) is at best moderate, leading to the “clinico-radiological paradox”, influenced by man...
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Neuroimaging Findings in Mild Cognitive Impairment
The clinical construct of mild cognitive impairment (MCI) identifies a syndrome of cognitive deficit which is not significant enough to interfere with daily activities, whose fate is unpredictable without esta...
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Article
Degree of microstructural changes within T1-SE versus T1-GE hypointense lesions in multiple sclerosis: relevance for the definition of “black holes”
To retrospectively evaluate the different performances of T1-SE and T1-GE sequences in detecting hypointense lesions in multiple sclerosis (MS), to quantify the degree of microstructural damage within lesions ...
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Article
Open Access123I-FP-CIT SPECT validation of nigro-putaminal MRI tractography in dementia with Lewy bodies
Assessment of nigrostriatal degeneration is a key element to discriminate between dementia with Lewy bodies (DLB) and Alzheimer disease (AD), and it is often evaluated using ioflupane (123I-FP-CIT) single-photon ...
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Open AccessMolecular imaging of multiple sclerosis: from the clinical demand to novel radiotracers
Brain PET imaging with different tracers is mainly clinically used in the field of neurodegenerative diseases and brain tumors. In recent years, the potential usefulness of PET has also gained attention in the...
