Skip to main content

and
  1. No Access

    Article

    Blockade of CTLA-4 promotes the development of effector CD8+ T lymphocytes and the therapeutic effect of vaccination with an attenuated protozoan expressing NY-ESO-1

    The development of cancer immunotherapy has long been a challenge. Here, we report that prophylactic vaccination with a highly attenuated Trypanosoma cruzi strain expressing NY-ESO-1 (CL-14-NY-ESO-1) induces bot...

    Luara Isabela dos Santos, Bruno Galvão-Filho in Cancer Immunology, Immunotherapy (2015)