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Article
Open AccessCentral domain deletions affect the SAXS solution structure and function of Yeast Hsp40 proteins Sis1 and Ydj1
Ydj1 and Sis1 are structurally and functionally distinct Hsp40 proteins of the yeast cytosol. Sis1 is an essential gene whereas the ydj1 gene is essential for growth at elevated temperatures and cannot complement...
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Article
Open AccessHuman Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain
The NIMA-related kinases (Neks) are widespread among eukaryotes. In mammalians they represent an evolutionarily conserved family of 11 serine/threonine kinases, with 40-45% amino acid sequence identity to the Asp...