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  1. Article

    Open Access

    Sunitinib added to FOLFIRI versus FOLFIRI in patients with chemorefractory advanced adenocarcinoma of the stomach or lower esophagus: a randomized, placebo-controlled phase II AIO trial with serum biomarker program

    As a multi-targeted anti-angiogenic receptor tyrosine kinase (RTK) inhibitor sunitinib (SUN) has been established for renal cancer and gastrointestinal stromal tumors. In advanced refractory esophagogastric ca...

    Markus Moehler, Irina Gepfner-Tuma, Annett Maderer, Peter C. Thuss-Patience in BMC Cancer (2016)

  2. Article

    Open Access

    LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases--a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial

    15-20% of all patients initially diagnosed with colorectal cancer develop metastatic disease and surgical resection remains the only potentially curative treatment available. Current 5-year survival following ...

    Carl Christoph Schimanski, Markus Möhler, Michael Schön, Eric van Cutsem in BMC Cancer (2012)

  3. Article

    Open Access

    Survival after chemotherapy and/or radiotherapy versus self-expanding metal stent insertion in the setting of inoperable esophageal cancer: a case-control study

    Our aim was to compare survival of the various treatment modality groups of chemotherapy and/or radiotherapy in relation to SEMS (self-expanding metal stents) in a retrospective case-control study. We have mad...

    George Sgourakis, Ines Gockel, Constantine Karaliotas, Markus Moehler in BMC Cancer (2012)