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  1. Article

    Open Access

    Identification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat

    The number of spikelets per spike is a key trait that affects the yield of bread wheat (Triticum aestivum L.). Identification of the QTL for spikelets per spike and its genetic effects that could be used in molec...

    Zhiqiang Wang, Haojie Li, **njian Zhou, Yuzhou Mou, Ying Zhang, Lang Yu in BMC Genomics (2024)

  2. Article

    Open Access

    IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer

    Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinica...

    **g Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Jihui Zhu in BMC Medicine (2024)

  3. Article

    Open Access

    Development and validation of a scale for the assessment of the knowledge-attitude-practice of parents towards children snoring

    Children Snoring is a common childhood disorder that affects the growth and development of children and is detrimental to their health. Increasing awareness of Children Snoring among parents is important.

    Siyan Guo, **aoyue Hu, **aokai Wang, Hongyan Tie, Qiujun Zhang in BMC Primary Care (2024)

  4. Article

    Open Access

    Outcomes of allogeneic hematopoietic stem cell transplantation in R/R DLBCL patients with failure of CAR-T therapy

    From October 2017 to June 2022, we retrospectively report outcomes of R/R DLBCL patients with failure of CAR-T therapy, then receiving allo-HSCT. Among 10 patients, 5 were males and 5 females, with a median ag...

    Mengya Cong, Sicheng Ai, Liqing Kang, Mao ** in Experimental Hematology & Oncology (2024)

  5. Article

    Open Access

    Development and external validation of the multichannel deep learning model based on unenhanced CT for differentiating fat-poor angiomyolipoma from renal cell carcinoma: a two-center retrospective study

    There are undetectable levels of fat in fat-poor angiomyolipoma. Thus, it is often misdiagnosed as renal cell carcinoma. We aimed to develop and evaluate a multichannel deep learning model for differentiating ...

    Haohua Yao, Li Tian, ** Liu, Shurong Li in Journal of Cancer Research and Clinical On… (2023)

  6. Article

    Open Access

    CREB1-driven CXCR4hi neutrophils promote skin inflammation in mouse models and human patients

    Neutrophils have a pathogenic function in inflammation via releasing pro-inflammatory mediators or neutrophil extracellular traps (NETs). However, their heterogeneity and pro-inflammatory mechanisms remain unc...

    Jiaoling Chen, Yaxing Bai, Ke Xue, Zhiguo Li, Zhenlai Zhu in Nature Communications (2023)

  7. Article

    Open Access

    Sohlh1 and Lhx8 are prominent biomarkers to estimate the primordial follicle pool in mice

    Efficient evaluation of the primordial follicle pool (PFP) of mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a ...

    Li Liu, Biting Liu, Lian Wang, Caixia Li in Reproductive Biology and Endocrinology (2023)

  8. Article

    Open Access

    Which one is better for refractory/relapsed acute B-cell lymphoblastic leukemia: Single-target (CD19) or dual-target (tandem or sequential CD19/CD22) CAR T-cell therapy?

    CD19 chimeric antigen receptor (CAR) T-cell therapy has shown great success against B-cell acute lymphoblastic leukemia (B-ALL). Tandem and sequential CD19/CD22 dual-target CAR T-cell therapies have been devel...

    Sining Liu, **nyue Zhang, Hai** Dai, Wei Cui, Jia Yin, Zheng Li in Blood Cancer Journal (2023)

  9. Article

    Open Access

    Adipose-derived stem cells promote the repair of chemotherapy-induced premature ovarian failure by inhibiting granulosa cells apoptosis and senescence

    Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used t...

    Guihai Ai, Meng Meng, **g Guo, Caixia Li, Jihui Zhu in Stem Cell Research & Therapy (2023)

  10. Article

    Open Access

    Differences in clinical characteristics and outcomes between patients with grade 3a and grades 1–2 follicular lymphoma: a real-world multicenter study

    The difference between clinical characteristics and outcomes between follicular lymphoma grade 1–2 (FL1-2) and FL3a defined pathologically remains unclear, resulting in uncertainty how to treat FL3a. However, ...

    Jie Zha, Qinwei Chen, **g**g Ye, Haifeng Yu, Shuhua Yi, Zhong Zheng in Biomarker Research (2023)

  11. Article

    Open Access

    Author Correction: Atomically dispersed cobalt catalyst anchored on nitrogen-doped carbon nanosheets for lithium-oxygen batteries

    Peng Wang, Yingying Ren, Rutao Wang, Peng Zhang, Mingjie Ding in Nature Communications (2022)

  12. Article

    Open Access

    Deep learning to diagnose Hashimoto’s thyroiditis from sonographic images

    Hashimoto’s thyroiditis (HT) is the main cause of hypothyroidism. We develop a deep learning model called HTNet for diagnosis of HT by training on 106,513 thyroid ultrasound images from 17,934 patients and tes...

    Qiang Zhang, Sheng Zhang, Yi Pan, Lin Sun, Jianxin Li, Yu Qiao in Nature Communications (2022)

  13. Article

    Open Access

    Chimeric antigen receptors containing the OX40 signalling domain enhance the persistence of T cells even under repeated stimulation with multiple myeloma target cells

    Persistence of CAR-T cell function is associated with relapse rate after CAR-T therapy, while co-stimulatory agents are highly concerned with the persistence of CAR-T cells. In this study, we designed and cons...

    **gwen Tan, Yujie Jia, Meixia Zhou, Chengcheng Fu in Journal of Hematology & Oncology (2022)

  14. Article

    Open Access

    Microwave pyrolysis of sludge: a review

    As an environmentally friendly energy recovery technology, microwave pyrolysis has huge development potential in sludge resource treatment. This paper comprehensively reviews the progress of microwave pyrolysi...

    Shaobai Li, Caixia Li, Zhiguo Shao in Sustainable Environment Research (2022)

  15. Article

    Retraction Note: Differentiation analysis for estimating individual ancestry from the Tibetan Plateau by an archaic altitude adaptation EPAS1 haplotype among East Asian populations

    Li Jiang, Jianxiong Peng, Meisha Huang, **g Liu in International Journal of Legal Medicine (2021)

  16. Article

    Retraction Note: Predicting adult height from DNA variants in a European-Asian admixed population

    **aoxi **g, Yanan Sun, Wenting Zhao in International Journal of Legal Medicine (2021)

  17. Article

    Open Access

    Epstein–Barr virus and cytomegalovirus reactivation after allogeneic hematopoietic cell transplantation in patients with non–Hodgkin lymphoma: the prevalence and impacts on outcomes

    Epstein–Barr virus (EBV) and cytomegalovirus (CMV) reactivations are common complications after allogeneic hematopoietic cell transplantation (allo-HCT), but data focusing on non–Hodgkin lymphoma (NHL) are lim...

    Yiyang Ding, Yuhua Ru, Tiemei Song, Lingchuan Guo, **ang Zhang in Annals of Hematology (2021)

  18. Article

    Retraction Note: EDAR, LYPLAL1, PRDM16, PAX3, DKK1, TNFSF12, CACNA2D3, and SUPT3H gene variants influence facial morphology in a Eurasian population

    Yi Li, Wenting Zhao, Dan Li, **anming Tao, Ziyi **ong, **g Liu in Human Genetics (2021)

  19. Article

    Open Access

    Phenotypic and genetic variation in phosphorus-deficiency-tolerance traits in Chinese wheat landraces

    Phosphorus deficiency is a major limiting factors for affecting crop production globally. To understand the genetic variation of phosphorus-deficiency-tolerance, a total of 15 seedling traits were evaluated am...

    Yu Lin, Guangdeng Chen, Haiyan Hu, **lan Yang, Zhengli Zhang in BMC Plant Biology (2020)

  20. Article

    Open Access

    Association between ceramides and coronary artery stenosis in patients with coronary artery disease

    Coronary artery stenosis induces heart diseases including acute coronary syndrome (ACS). Some studies reported the ceramide species are associated with the ACS and major adverse cardia and cerebrovascular even...

    Chenchen Tu, Lan **e, Zhenjie Wang, Lili Zhang, Hongmei Wu in Lipids in Health and Disease (2020)

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