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Article
Open AccessIdentification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat
The number of spikelets per spike is a key trait that affects the yield of bread wheat (Triticum aestivum L.). Identification of the QTL for spikelets per spike and its genetic effects that could be used in molec...
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Article
Open AccessIL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer
Tumor-infiltrating lymphocyte (TIL) therapy has been restricted by intensive lymphodepletion and high-dose intravenous interleukin-2 (IL-2) administration. To address these limitations, we conducted preclinica...
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Article
Open AccessDevelopment and validation of a scale for the assessment of the knowledge-attitude-practice of parents towards children snoring
Children Snoring is a common childhood disorder that affects the growth and development of children and is detrimental to their health. Increasing awareness of Children Snoring among parents is important.
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Article
Au nanoparticles on N-doped carbon modified carbon cloth for flexible sodium metal batteries
A novel flexible sodium metal anodes were designed and fabricated via composite gold nanoparticles with N-doped carbon nanorods on carbon cloths. As-prepared anodes exhibit low overpotential and stable sodium ...
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Article
Influence of the Omicron outbreak on allo-HSCT recipients in China: a single-center short-term observational cohort study
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Open AccessOutcomes of allogeneic hematopoietic stem cell transplantation in R/R DLBCL patients with failure of CAR-T therapy
From October 2017 to June 2022, we retrospectively report outcomes of R/R DLBCL patients with failure of CAR-T therapy, then receiving allo-HSCT. Among 10 patients, 5 were males and 5 females, with a median ag...
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Article
Photocatalytic performance of inverse-opal g-carbon nitride and bismuth oxide compositing microstructures
The development of visible-light photocatalytic materials in porous morphology with suitable photon management is significant for energy utilization and environmental protection. g-C3N4 and Bi2O3 are both typical...
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Article
Influence of alkyl linkers on the anti-breast cancer activity of dihydroartemisinin-isatin hybrids
To investigate the impact of alkyl linkers of different lengths between dihydroartemisinin and isatin moieties on the anti-breast cancer activity, a series of twenty dihydroartemisinin-isatin hybrids with thre...
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Article
Open AccessDevelopment and external validation of the multichannel deep learning model based on unenhanced CT for differentiating fat-poor angiomyolipoma from renal cell carcinoma: a two-center retrospective study
There are undetectable levels of fat in fat-poor angiomyolipoma. Thus, it is often misdiagnosed as renal cell carcinoma. We aimed to develop and evaluate a multichannel deep learning model for differentiating ...
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Article
Effects and Feasibility of a Mindfulness-Based Guqin Music Intervention During Pregnancy on Postpartum Anxiety and Depression: A Pilot Randomized Controlled Trial
This study aimed to test the effects and feasibility of a mindfulness-based Guqin music intervention (MBGI), administered during pregnancy, on postpartum anxiety and depression.
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Article
Open AccessCREB1-driven CXCR4hi neutrophils promote skin inflammation in mouse models and human patients
Neutrophils have a pathogenic function in inflammation via releasing pro-inflammatory mediators or neutrophil extracellular traps (NETs). However, their heterogeneity and pro-inflammatory mechanisms remain unc...
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Article
Open AccessSohlh1 and Lhx8 are prominent biomarkers to estimate the primordial follicle pool in mice
Efficient evaluation of the primordial follicle pool (PFP) of mammalian models is an essential subject in biomedical research relating to ovarian physiology and pathogenesis. Our recent study has identified a ...
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Article
Open AccessWhich one is better for refractory/relapsed acute B-cell lymphoblastic leukemia: Single-target (CD19) or dual-target (tandem or sequential CD19/CD22) CAR T-cell therapy?
CD19 chimeric antigen receptor (CAR) T-cell therapy has shown great success against B-cell acute lymphoblastic leukemia (B-ALL). Tandem and sequential CD19/CD22 dual-target CAR T-cell therapies have been devel...
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Article
Open AccessAdipose-derived stem cells promote the repair of chemotherapy-induced premature ovarian failure by inhibiting granulosa cells apoptosis and senescence
Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used t...
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Article
Genome-wide identification and characterization of circRNAs in wheat tiller
This study found that the intergenic circRNAs of wheat were more abundant than those of other plants. More importantly, a circRNA-mediated network associated with tillering was constructed for the first time.
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Article
Genome-wide association analysis of Fusarium crown rot resistance in Chinese wheat landraces
A novel locus for Fusarium crown rot (FCR) resistance was identified on chromosome 1B at 641.36–645.13 Mb using GWAS and could averagely increase 39.66% of FCR resistance in a biparental population.
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Article
Evaluation of the Liberation Characteristic of Coarse Middling Coking Coal by Size-Density Fractionation
In this paper, the size-density distribution of coarse middling coking coal (CMCC) with different grinding fineness and flotation concentrates was investigated. Then, the flotation behaviors and liberation cha...
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Article
Autologous hematopoietic stem cell transplantation activity for lymphoma and multiple myeloma in China
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Article
Reclamation of heavy coastal silt saline soil and optimal tomato production through a drip irrigation system with saline water
It has always been challenged to improve heavy coastal silt saline soil for crop productions through establishing an irrigation system with saline water. This study was aimed to investigate the effect of the e...
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Article
Open AccessDifferences in clinical characteristics and outcomes between patients with grade 3a and grades 1–2 follicular lymphoma: a real-world multicenter study
The difference between clinical characteristics and outcomes between follicular lymphoma grade 1–2 (FL1-2) and FL3a defined pathologically remains unclear, resulting in uncertainty how to treat FL3a. However, ...
