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Article
Netherlands Society for Microbiology Meeting at Utrecht on 23 May 1969
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Article
Metabolism of glycerol-3-phosphate and phospholipids in a temperature-sensitive lysis mutant ofEscherichia coli
Phospholipid metabolism in a temperature-sensitive lysis mutant ofEscherichia coli has been investigated. The incorporation of32P into the phospholipids of this mutant was negligible, not only at the non-permissi...
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Article
Map** of a gene for a major outer membrane protein ofEscherichia coli K12 with the aid of a newly isolated bacteriophage
A method is described for the enrichment of phages which can adsorb to a specific determinant of bacterial cell surfaces. A phage was isolated which adsorbs toE. coli cells containing the “major outer membrane” p...
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Chapter and Conference Paper
A congruence theorem for structured operational semantics with predicates
We proposed a syntactical format, the path format, for structured operational semantics in which predicates may occur. We proved that strong bisimulation is a congruence for all the operators that can be defined ...
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Chapter and Conference Paper
A congruence theorem for structured operational semantics with predicates and negative premises
We proposed a syntactic format, the panth format, for structured operational semantics in which besides ordinary transitions also predicates, negated predicates, and negative transitions may occur such that if th...
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Chapter and Conference Paper
A congruence theorem for structured operational semantics with predicates and negative premises
We proposed a syntactic format, the panth format, for structured operational semantics in which besides ordinary transitions also predicates, negated predicates, and negative transitions may occur such that if th...
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Chapter
Evolutionary software engineering: a component-based approach
A software industry producing high-quality components that can be reused in many ways is an—unfulfilled—dream as old as the field of “software engineering” itself. In this paper we present an evolutionary appr...
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Article
Towards automated modification of legacy assets
In this paper we argue that there is a necessity for automating modifications to legacy assets. We propose a five layered process for the introduction and employment of tool support that enables automated modi...
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Article
Total pelvic exenteration for primary locally advanced and recurrent rectal cancer
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Article
Pre-operative radiotherapy improves outcome of multimodality treatment in recurrent rectal cancer
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Article
9210: The Zip Code of Another IT-Soap
Nine-to-ten (9210) refers to the problem that the Dutch banks are running out of 9-digit bank account numbers and need to convert to 10-digit numbers. At the same time, the Dutch government wants bank account ...
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Article
Open AccessTotal Pelvic Exenteration for Primary and Recurrent Malignancies
Complete resection is the most important prognostic factor in surgery for pelvic tumors. In locally advanced and recurrent pelvic malignancies, radical margins are sometimes difficult to obtain because of clos...
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Article
Open AccessLocal excision of rectal cancer afterchemoradiation: feasibility depends on the primary stage
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Chapter and Conference Paper
Simulation-Based Performance Analysis of Channel-Based Coordination Models
Quantifying the performance of component-based or service-oriented systems is a complex task, e.g., it is non-trivial to calculate the end-to-end quality of service of a composite Web service. An established a...
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Chapter and Conference Paper
Isolated Hypoxic Liver Perfusion with Melfalan in Humans and Its Anesthesiologic Aspects
This is the first detailed description from the anesthesiologic management during isolated hypoxic hepatic perfusion (IHHP), a complex way of regional cancer therapy. During IHHP, there is full clam** of the...
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Article
Open AccessEndothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells
Mature circulating endothelial cells (CEC) are surrogate markers of endothelial damage. CEC measured in patients with advanced cancer are thought not only to derive from damaged normal vasculature (n-CEC), but...
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Article
Open AccessPrognostic value of circulating tumour cells for early recurrence after resection of colorectal liver metastases
Despite good outcomes for many, a substantial group of patients undergoing metastasectomy for isolated liver metastases from colorectal cancer (CRC) experience early recurrence. We have investigated whether ci...
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Article
Open AccessResponse to chemotherapy in patients with recurrent rectal cancer in previously irradiated area
Tumor lesions in previously irradiated area may have a less favorable response to chemotherapy compared to tumor sites outside the radiation field. The aim of the present study was to evaluate the response to ...
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Article
Open AccessMiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing
MicroRNAs (miRs) have been recognized as promising biomarkers. It is unknown to what extent tumor-derived miRs are differentially expressed between primary colorectal cancers (pCRCs) and metastatic lesions, an...
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Article
Open AccessTUmor-volume to breast-volume RAtio for improving COSmetic results in breast cancer patients (TURACOS); a randomized controlled trial
Cosmetic result following breast conserving surgery (BCS) for cancer influences quality of life and psychosocial functioning in breast cancer patients. A preoperative prediction of expected cosmetic result fol...
