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Article
Open AccessIdentification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer
Over the past years, some members of the family of suppressor of cytokine signalling (SOCS) proteins have emerged as potential tumour suppressors. This study aimed at investigating the clinical significance of...
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Article
Evidence of founder chromosomes in fragile X syndrome
The mutation responsible for fragile X syndrome and myotonic dystrophy involves the amplification of a simple trinucleotide repeat sequence, which increases in successive generations of affected pedigrees acco...
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Article
Independent control of selected insulin-sensitive cell membrane and intracellular functions — the linkage of cell membrane and intracellular events controlled by insulin
Brief treatment of rat adipocytes with low concentration of trypsin activated both cell membrane and intracellular insulin-sensitive functions in marked contrast to H2O2 (1), increase in pH, and oxidized glutathi...
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Article
Chemical mechanism of insulin action via proteolytic formation of mediator peptides