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Article
Open AccessTeaching breast ultrasound skills including core-needle biopsies on a phantom enhances undergraduate student’s knowledge and learning satisfaction
To investigate whether a training program on breast ultrasound skills including core-needle biopsies to undergraduate students can improve medical knowledge and learning satisfaction.
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Article
Efficacy and safety of two post-operative drains: results of a prospectively randomized clinical study in breast cancer patients after breast conserving surgery
To compare the efficacy and safety of two post-operative drains in breast cancer patients after breast conserving surgery.
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Article
Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene?
Genome-wide association studies have identified and repeatedly confirmed the association of rs3197999 in MST1 with inflammatory bowel disease (IBD). However, the underlying pathophysiology remains unclear. rs3197...
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Article
ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression
Tumor cells adaptation to severe oxygen deprivation (hypoxia) plays a major role in tumor progression. The transcription factor HIF-1 (hypoxia-inducible factor 1), whose α-subunit is stabilized under hypoxic c...
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Article
Population fragmentation leads to isolation by distance but not genetic impoverishment in the philopatric Lesser Kestrel: a comparison with the widespread and sympatric Eurasian Kestrel
Population fragmentation is a widespread phenomenon usually associated with human activity. As a result of habitat transformation, the philopatric and steppe-specialist Lesser Kestrel Falco naumanni underwent a s...
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Article
Acid sphingomyelinase deficiency protects from cisplatin-induced gastrointestinal damage
Cisplatin is one of the most effectively used chemotherapeutic agents for cancer treatment. However, in humans, important cytotoxic side effects are observed including dose-limiting renal damage and profound g...
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Article
Chemical defence in a sawfly: genetic components of variation in relevant life-history traits
Larvae of several tenthredinid sawfly species readily release droplets of haemolymph through their integument when attacked by predators. This defence mechanism via ‘bleeding’ is characterised by a low integum...
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Article
The cyo operon of Pseudomonas putida is involved in carbon catabolite repression of phenol degradation
A bicistronic reporter consisting of the promoterless genes aacC1 (conferring gentamycin resistance) and lacZ fused to the catabolic promoter of the phenol degradation genes was used to identify and analyse muta...
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Article
The inverted repeats of IS1384, a newly described insertion sequence from Pseudomonas putida strain H, represent the specific target for integration of IS1383
Analysis of a region on plasmid pPGH1 from Pseudomonas putida strain H that is flanked by two copies of IS1383 has revealed an additional element with the typical features of a bacterial insertion sequence. This...
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Article
The transposable elements resident on the plasmids of Pseudomonas putida strain H, Tn5501 and Tn5502, are cryptic transposons of the Tn3 family
Genes for (methyl)phenol degradation in Pseudomonas putida strain H (phl genes) are located on the plasmid pPGH1. Adjacent to the phl catabolic operon we identified a cryptic transposon, Tn5501, of the Tn3 famil...
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Article
Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression
Active T cell suicide (apoptosis) is supposed to be involved in the CD4+ T cell depletion in the course of HIV infection. We investigated the expression of the apoptosis-related antigen Fas on CD4+ T cells from 2...
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Chapter and Conference Paper
RFLP Standardization Report for 210H/MspI
The 210H/MspI system identified six standard fragments in the core cell lines as shown in Table 1 and Figure 1. Much of the data received for this system was difficult to interpret because all the fragments we...
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Chapter and Conference Paper
RFLP Standardization Report for C4/MspI
The panel of core cell lines cut with restriction enzyme MspI and hybridized with the C4 probe revealed a very simple pattern (Fig. 1). Two fragments were identified, of which only the first was polymorphic (1...
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Chapter and Conference Paper
RFLP Standardization Report for Class I/MspI
The class I/MspI system showed extensive polymorphism, identifying 21 fragments on the core cell lines (Table 1 and Fig. 1). However, the large number of bands made interpretation of the data difficult despite...
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Chapter and Conference Paper
RFLP Standardization Report for DP Alpha/MspI
The DP alpha/MspI system was found to be relatively polymorphic, identifying 11 standard fragments in the core cell lines as shown in Figure 1 (band number 11 not shown). Fragment number 9 (1.02 kb) was the on...
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Chapter and Conference Paper
RFLP Standardization Report for BF/MspI
The Bf/MspI system identified a simple pattern of three fragments (Table 1). Standard fragments 1 and 2 were constant throughout the core cell lines. Fragment 3 was found to be polymorphic, but of low molecula...
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Chapter and Conference Paper
RFLP Standardization Report for DR Alpha/MspI
Three standard bands were recognized in the DR alpha/MspI system (Table 1 and Fig. 1). The resolution of fragments 1 and 2 on some autoradiographs was not good enough to allow easy interpretation producing dis...
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Chapter and Conference Paper
RFLP Standardization Report for C2/MspI
The C2/MspI system identified three standard fragments in the core cell lines (Fig. 1 and Table 1). Fragments 1 (2.30 kb) and 2 (1.79 kb) were found to be polymorphic, while fragment 3 (1.53 kb) was constant. ...
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Chapter and Conference Paper
RFLP Standardization Report For DQ Alpha/MspI
The core cell lines revealed 11 standard fragments in the DQ alpha/Msp1 system as shown in Figure 1. A fragment between standard bands 4 and 5 (at approximately 5.19 kb) has been reported by some laboratories,...
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Chapter and Conference Paper
Antigen Society #15 Report (Bw4 and Bw6)
During the Tenth Workshop, 27 anti-sera in the Antigen Society and 22 anti-sera in the Core serology serum set were provided for the serologic analysis of the supertypic HLA-B locus specificities Bw4 and Bw6. ...