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Article
Open AccessUsage of a graph database for the selection of sterile items in the OR
In this work, we present a subsystem of a robotic circulating nurse, that produces recommendations for the next supplied sterile item based on incomplete requests from the sterile OR staff, the current situati...
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Open AccessComparison of surgical techniques for optimal lead placement in sacral neuromodulation: a cadaver study
Sacral neuromodulation (SNM) is a common treatment for patients with urinary and faecal incontinence. A close contact of the tined lead electrode with the targeted nerve is likely to improve functional outcome.
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Article
Open AccessCyclotron production and radiochemical purification of terbium-155 for SPECT imaging
Terbium-155 [T1/2 = 5.32 d, Eγ = 87 keV (32%) 105 keV (25%)] is an interesting radionuclide suitable for single photon emission computed tomography (SPECT) imaging with potential application in the diagnosis of o...
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Article
Open AccessTeaching breast ultrasound skills including core-needle biopsies on a phantom enhances undergraduate student’s knowledge and learning satisfaction
To investigate whether a training program on breast ultrasound skills including core-needle biopsies to undergraduate students can improve medical knowledge and learning satisfaction.
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Article
Open AccessStandardized fluoroscopy-guided implantation technique enables optimal electrode placement in sacral neuromodulation: a cadaver study
Sacral neuromodulation (SNM) is an established treatment option for patients with faecal incontinence. The location of the stimulating electrode is considered to be essential for treatment success. The purpose...
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Open AccessEstablishment of a clinical SPECT/CT protocol for imaging of 161Tb
It has been proposed, and preclinically demonstrated, that 161Tb is a better alternative to 177Lu for the treatment of small prostate cancer lesions due to its high emission of low-energy electrons. 161Tb also em...
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Article
Efficacy and safety of two post-operative drains: results of a prospectively randomized clinical study in breast cancer patients after breast conserving surgery
To compare the efficacy and safety of two post-operative drains in breast cancer patients after breast conserving surgery.
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Article
A gastrointestinal stromal tumour mimicking solid pseudopapillary neoplasia of the pancreas—a case report
Diagnosis of large, heterogenous lesions of the pancreas with solid and cystic components is often challenging. The spectrum of differential diagnoses is broad, and clinical as well as radiological findings ma...
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Article
Directionality of non-permissive HLA-DPB1 T-cell epitope group mismatches does not improve clinical risk stratification in 8/8 matched unrelated donor hematopoietic cell transplantation
In 8/8 HLA-matched unrelated donor (UD) hematopoietic cell transplants (HCT), HLA-DPB1 mismatches between alleles from different T-cell epitope (TCE) groups (non-permissive mismatches) are associated with sign...
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Article
YKL-40 in allogeneic hematopoietic cell transplantation after AML and myelodysplastic syndrome
YKL-40, also called chitinase-3-like-1 protein, is an inflammatory biomarker that has been associated with disease severity in inflammatory and malignant diseases, including AML, multiple myeloma and lymphomas...
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Article
Open AccessEarly Endothelial Progenitor Cells (eEPCs) in systemic sclerosis (SSc) - dynamics of cellular regeneration and mesenchymal transdifferentiation
Patients with systemic sclerosis (SSc) are endagered by tissue fibrosis and by microvasculopathy, with the latter caused by endothelial cell expansion/proliferation. SSc-associated fibrosis potentially results...
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Open AccessRuling out nosocomial transmission of Cryptosporidium in a renal transplantation unit: case report
Cryptosporidium spp. is a ubiquitous parasite affecting humans as well as domestic and wild vertebrates, causing diarrhea in both immunocompetent and immunocompromised hosts worldwide....
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Article
Allogeneic hematopoietic cell transplantation as curative therapy for non-transformed follicular lymphomas
Allogeneic hematopoietic cell transplantation (HCT) offers the chance of cure for patients with non-transformed follicular lymphoma (FL), but is associated with the risk of non-relapse mortality (NRM). The aim...
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Article
Predicting in-hospital mortality using routine parameters in unselected nonsurgical emergency department patients
To assure adequate and efficient treatment in the emergency department (ED) despite increasing patient numbers, early risk stratification might be helpful for directing resource allocation.
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Article
Related hematopoietic cell donor care: is there a role for unrelated donor registries?
In almost half of allogeneic hematopoietic progenitor cell (HPC) transplants, a related donor (RD) is used, yet a lack of standardized guidelines means that their care is heterogeneous. Changes to regulatory s...
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3D visualization of the regional differences
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Article
Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity
Autism is a heritable disorder, with over 250 associated genes identified to date, yet no single gene accounts for >1–2% of cases. The clinical presentation, behavioural symptoms, imaging and histopathology fi...
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Article
Comparing the outcomes between Chopart, Lisfranc and multiple metatarsal shaft fractures
Complex midfoot injuries could lead to severe functional impairment of mobility and quality of daily living. Aim of this study was to compare the clinical and functional outcomes of Chopart, Lisfranc fractures...
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Article
Open AccessHematological profile of East African short-horn zebu calves from birth to 51 weeks of age
This paper is the first attempt to accurately describe the hematological parameters for any African breed of cattle, by capturing the changes in these parameters over the first 12 months of an animal’s life us...
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Article
ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression
Tumor cells adaptation to severe oxygen deprivation (hypoxia) plays a major role in tumor progression. The transcription factor HIF-1 (hypoxia-inducible factor 1), whose α-subunit is stabilized under hypoxic c...