23 Result(s)
within
C. Muller
Biomedicine
Human Genetics
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Article
Inflammatory bowel disease (IBD) locus 12: is glutathione peroxidase-1 (GPX1) the relevant gene?
Genome-wide association studies have identified and repeatedly confirmed the association of rs3197999 in MST1 with inflammatory bowel disease (IBD). However, the underlying pathophysiology remains unclear. rs3197...
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Article
Population fragmentation leads to isolation by distance but not genetic impoverishment in the philopatric Lesser Kestrel: a comparison with the widespread and sympatric Eurasian Kestrel
Population fragmentation is a widespread phenomenon usually associated with human activity. As a result of habitat transformation, the philopatric and steppe-specialist Lesser Kestrel Falco naumanni underwent a s...
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Article
Chemical defence in a sawfly: genetic components of variation in relevant life-history traits
Larvae of several tenthredinid sawfly species readily release droplets of haemolymph through their integument when attacked by predators. This defence mechanism via ‘bleeding’ is characterised by a low integum...
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Article
Fas (CD95) expression on CD4+ T cells from HIV-infected patients increases with disease progression
Active T cell suicide (apoptosis) is supposed to be involved in the CD4+ T cell depletion in the course of HIV infection. We investigated the expression of the apoptosis-related antigen Fas on CD4+ T cells from 2...
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Article
Prostaglandin-Interaktion in der menschlichen Leber
The binding of prostaglandin (PG) E1 and Iloprost, a chemically stable PGI2-analogue, to purified plasma cell membranes (LPZM) from liver tissue samples obtained at surgery revealed heterogeneity of the bindin...
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Chapter and Conference Paper
RFLP Standardization Report for 210H/MspI
The 210H/MspI system identified six standard fragments in the core cell lines as shown in Table 1 and Figure 1. Much of the data received for this system was difficult to interpret because all the fragments we...
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Chapter and Conference Paper
RFLP Standardization Report for C4/MspI
The panel of core cell lines cut with restriction enzyme MspI and hybridized with the C4 probe revealed a very simple pattern (Fig. 1). Two fragments were identified, of which only the first was polymorphic (1...
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Chapter and Conference Paper
RFLP Standardization Report for Class I/MspI
The class I/MspI system showed extensive polymorphism, identifying 21 fragments on the core cell lines (Table 1 and Fig. 1). However, the large number of bands made interpretation of the data difficult despite...
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Chapter and Conference Paper
RFLP Standardization Report for DP Alpha/MspI
The DP alpha/MspI system was found to be relatively polymorphic, identifying 11 standard fragments in the core cell lines as shown in Figure 1 (band number 11 not shown). Fragment number 9 (1.02 kb) was the on...
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Chapter and Conference Paper
RFLP Standardization Report for BF/MspI
The Bf/MspI system identified a simple pattern of three fragments (Table 1). Standard fragments 1 and 2 were constant throughout the core cell lines. Fragment 3 was found to be polymorphic, but of low molecula...
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Chapter and Conference Paper
RFLP Standardization Report for DR Alpha/MspI
Three standard bands were recognized in the DR alpha/MspI system (Table 1 and Fig. 1). The resolution of fragments 1 and 2 on some autoradiographs was not good enough to allow easy interpretation producing dis...
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Chapter and Conference Paper
RFLP Standardization Report for C2/MspI
The C2/MspI system identified three standard fragments in the core cell lines (Fig. 1 and Table 1). Fragments 1 (2.30 kb) and 2 (1.79 kb) were found to be polymorphic, while fragment 3 (1.53 kb) was constant. ...
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Chapter and Conference Paper
RFLP Standardization Report For DQ Alpha/MspI
The core cell lines revealed 11 standard fragments in the DQ alpha/Msp1 system as shown in Figure 1. A fragment between standard bands 4 and 5 (at approximately 5.19 kb) has been reported by some laboratories,...
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Chapter and Conference Paper
Antigen Society #15 Report (Bw4 and Bw6)
During the Tenth Workshop, 27 anti-sera in the Antigen Society and 22 anti-sera in the Core serology serum set were provided for the serologic analysis of the supertypic HLA-B locus specificities Bw4 and Bw6. ...
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Chapter and Conference Paper
RFLP Standardization Report for DR Beta/MsPI
DRbeta/MspI blots were received from four laboratories. In spite of the standardized technique, the overall intensity of the blots and the number of fragments detected were somewhat variable. Marker bands were...
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Chapter and Conference Paper
RFLP Standardization Report for DQ Beta/MspI
DQ beta/MspI blots were received from four laboratories and were analyzed as detailed in the report on DR beta/MspI. The DQ beta/MspI system identified 22 fragments on the core cell lines (Table 1 and Figs. 1 ...
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Chapter and Conference Paper
RFLP Standardization Report for DP Beta/MspI
DP beta/MspI blots were received from four laboratories and were analyzed as detailed in the report on DR Beta/MspI. The DP beta/MspI system identified 20 fragments on the core cell lines (Figs. 1 and 2). Nine...
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Chapter and Conference Paper
Myasthenia Gravis: Joint Report
Previous studies have demonstrated the importance of immunogenetic factors in myasthenia gravis (MG) (Table 1). In Caucasoids, generalized MG (GMG) is associated with A1,B8,DR3 (1,8,3). This particular supraty...
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Article
Refinement of HLA gene map** with induced B-cell line mutants
The lymphoma cell line BJAB.B95.8.6 was gamma-irradiated to induce mutations of major histocompatibility complex (MHC) encoded genes. Cloned “wild-type” cells were phenotyped HLA-A1, A2, B 13, 1335, Bw4, Bw6, ...
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Article
Bone marrow transplantation for acute leukemia in second or subsequent remission
Twenty-one patients with acute leukemia in second to fifth remission were treated with bone marrow transplantation: 19 patients with transplants from HLA-matched siblings and two with transplants from identica...
