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Prognostic Factors and Treatment of Multiple Myeloma: Interest of a Cyclic Sequential Chemohormonotherapy Combining Cyclophosphamide, Melphalan, and Prednisone
In 1889, Kalher succeeded in establishing the relationship between Bence Jones proteinuria [27], discovered in 1845, and the bone “tumor,” called “multiple myeloma” by Rustisky in 1873 [51]. Later, in 1900, Wrigh...