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Clinical value of molecular subty** multiple myeloma using gene expression profiling

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  1. Article

    Open Access

    Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

    Myeloma is heterogeneous at the molecular level with subgroups of patients characterised by features of epigenetic dysregulation. Outcomes for myeloma patients have improved over the past few decades except fo...

    C Pawlyn, M D Bright, A F Buros, C K Stein, Z Walters, L I Aronson… in Blood Cancer Journal (2017)

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  2. Article

    Open Access

    Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker

    The purpose of this study is to identify prognostic markers and treatment targets using a clinically certified sequencing panel in multiple myeloma. We performed targeted sequencing of 578 individuals with pla...

    S S Chavan, J He, R Tytarenko, S Deshpande, P Patel, M Bailey… in Blood Cancer Journal (2017)

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