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Article
Maternal influence of prolyl endopeptidase on fat mass of adult progeny
Maternal genotype has lifetime effects on progeny, but few specific genes, and no proteases, are known to underlie maternal effects. Prolyl endopeptidase (PREP) is a serine protease with putative substrates th...
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Article
Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass
Gastric bypass surgery is the most commonly performed bariatric surgical procedure in the United States. Variable weight loss following this relatively standardized intervention has been reported. To date, a m...
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Article
Multiple linked mouse chromosome 7 loci influence body fat mass
BACKGROUND: Congenic mouse strains contain donor mouse strain DNA in genomes otherwise identical to a background strain. They can be used to identify defined chromosomal regions containing obesity genes with smal...
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Article
Uncoupling proteins-2 and 3 influence obesity and inflammation in transgenic mice
OBJECTIVE: To test the hypothesis that either uncoupling protein-2 UCP2 or UCP3 or both together influence obesity and inflammation in transgenic mice.
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Article
Association between Uncoupling Protein 2, Body Composition, and Resting Energy Expenditure in Lean and Obese African American, Asian, and Caucasian Children