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Chapter and Conference Paper
Analysis of Cardiopulmonary Function in Esophageal Cancer Patients Prior to Surgery
In Western Europe esophageal cancer comprises 5% of all gastrointestinal malignancies, and is most frequent in men older than 40 years of age. In 80% of the cases it is located in the middle and lower part of ...
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Article
Diamine oxidase as a marker of intestinal integrity in acute appendicitis
In the operative treatment of appendicitis the so called negative appendectomy is an important issue because of its increased morbidity. From the hypothesis that the intestinal diamine oxidase activity is a su...
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Article
Inhibition of human and canine diamine oxidase by drugs used in an intensive care unit: Relevance for clinical side effects?
Three hundred and forty-one drugs, commonly used in intensive care units (ICU), were chosen for an investigation of possible activation or inhibition of the histamine metabolizing enzyme diamine oxidase (DAO)....
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Article
Histamine content, diamine oxidase activity and histamine methyltransferase activity in human tissues: Fact or fictions?
To understand the role of histamine in the aetiology and pathogenesis of human diseases reliable data are urgently needed for the histamine content and for the activities of histamine-forming and-inactivating ...
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Article
The start of a programme for measuring diamine oxidase activity in biopsy specimens of human rectal mucosa
In human subjects, apart from in the kidney, diamine oxidase occurs mainly in the gut. Therefore this enzyme can be used as an indicator of intestinal integrity.
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Article
The influence of carcinoma growth on diamine oxidase activity in human gastrointestinal tract
The distribution of diamine oxidase (DAO) activity was studied in patients having no carcinoma disease. Besides in gut DAO occurred in high activity only in kidney and mesenteric lymph nodes.
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Article
Comparison of alterations in the histamine-diamine oxidase system during acute intestinal ischaemia in pigs, dogs and rabbits: Evidence for a uniform pathophysiological mechanism?
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Chapter and Conference Paper
Discussion
KUSCHE and STAHLKNECHT eloborated on the relation between neoplastic growth and polyamine metabolism. Diamine oxydase deaminates putrescine and thereby influences the concentrations of the polyamines putrescin...
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Article
Diamine oxidase activity in gastric and duodenal mucosa of man and other mammals with special reference to the pyloric junction
In the gastric mucosa of human subjects and of various mammals methylation was accepted as the main pathway of histamine catabolism. However, augmentation of gastric acid secretion by aminoguanidine, the stron...
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Article
Diamine oxidase activity and histamine release in dogs following acute mesenteric artery occlusion
Following superior mesenteric artery occlusion and revasclarization in dogs all animals died in a circulatory collapse state. However, pretreatment by aminoguanidine, the strong and specific inhibitor of diami...