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  1. Article

    Open Access

    Long-term metformin treatment in adolescents with obesity and insulin resistance, results of an open label extension study

    Off-label metformin is nowadays frequently used for the treatment of obesity in adolescents. However, studies on long-term metformin treatment in adolescents with obesity are scarce. Therefore, an 18 month ope...

    Y. E. Lentferink, M. P. van der Aa, E. G. A. H. van Mill… in Nutrition & Diabetes (2018)

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  2. Article

    Open Access

    Long-term treatment with metformin in obese, insulin-resistant adolescents: results of a randomized double-blinded placebo-controlled trial

    As adolescents with obesity and insulin resistance may be refractory to lifestyle intervention therapy alone, additional off-label metformin therapy is often used. In this study, the long-term efficacy and saf...

    M P van der Aa, M A J Elst, E M W van de Garde, E G A H van Mil… in Nutrition & Diabetes (2016)

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  3. Article

    298 Cd3+Cd4+-Lymphocytes as Biomarker Predicting the Outcome of Pediatric Haematopoietic Stem Cell Transplantation Recipients

    Introduction: Haematopoietic stem cell transplantation (HSCT) may be complicated by severe infectious complications, graft-versus-host disease (GvHD) and relapse/graft failures depending on the lymphocyte immu...

    I Bartelink, S V Belitser, C A J Knibbe, M Danhof, P J De Pagter… in Pediatric Research (2010)

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