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    Article

    Development of DNA delivery system using Pseudomonas exotoxin A and a DNA binding region of human DNA topoisomerase I

    Gene therapy is defined as the delivery of a functional gene for expression in somatic tissues with the intent to cure a disease. Thus, highly efficient gene transfer is essential for gene therapy. Receptor-m...

    T.-Y. Chen, C.-T. Hsu, K.-H. Chang, C.-Y. Ting… in Applied Microbiology and Biotechnology (2000)

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    Article

    Recombinant protein composed of Pseudomonas exotoxin A, outer membrane proteins I and F as vaccine against P. aeruginosa infection

    We have constructed a chimeric protein composed of the receptor binding and membrane translocation domains of Pseudomonas exotoxin A (PE) with the outer membrane proteins I and F, together designated as PEIF. Th...

    T.-Y. Chen, H.-F. Shang, T.-L. Chen, C.-P. Lin… in Applied Microbiology and Biotechnology (1999)