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Article

Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells

Standard therapy for acute promyelocytic leukaemia (APL) includes retinoic acid (all-trans retinoic acid (ATRA)), which promotes differentiation of promyelocytic blasts. Although co-administration of arsenic trio...

M Valenzuela, C Glorieux, J Stockis, B Sid, J M Sandoval… in British Journal of Cancer (2014)