21 Result(s)

Article

Impact of drug development on the use of stem cell transplantation: a report by the European Society for Blood and Marrow Transplantation (EBMT)

Hematopoietic stem cell transplantation (HSCT) is used with increasing frequency in Europe with 40 000 transplants reported in 2014. Transplant-related mortality remains high in allogeneic HSCT (10–20%); high-...

J R Passweg, H Baldomero, P Bader, C Bonini, S Cesaro… in Bone Marrow Transplantation (2017)

Article

Busulfan–Melphalan followed by autologous stem cell transplantation in patients with high-risk neuroblastoma or Ewing sarcoma: an exposed–unexposed study evaluating the clinical impact of the order of drug administration

M E Dourthe, N Ternès, D Gajda, A Paci, C Dufour, E Benhamou… in Bone Marrow Transplantation (2016)

Article

Busulfan–melphalan in high-risk neuroblastoma: the 30-year experience of a single institution

High-dose chemotherapy (HDC) was investigated in high-risk neuroblastoma (HR-NBL) to reduce the risk of relapse. We report the results of the 30-year experience of a cohort of patients with HR-NBL treated with...

S Proust-Houdemont, C Pasqualini, P Blanchard, C Dufour… in Bone Marrow Transplantation (2016)

Article

Characteristics and outcomes of aplastic anemia in HIV patients: a brief report from the severe aplastic anemia working party of the European Society of Blood and Bone Marrow Transplantation

S Pagliuca, L Gérard, A Kulasekararaj, M Eapen, D Boutboul… in Bone Marrow Transplantation (2016)

Article

Tandem high-dose chemotherapy with thiotepa and busulfan–melphalan and autologous stem cell transplantation in very high-risk neuroblastoma patients

High-risk neuroblastoma is characterised by poor long-term survival, especially for very high-risk (VHR) patients (poor response of metastases after induction therapy). We report the results of an intensified ...

C Pasqualini, C Dufour, G Goma, M-A Raquin, V Lapierre… in Bone Marrow Transplantation (2016)

Article

Recommendations on hematopoietic stem cell transplantation for inherited bone marrow failure syndromes

Allogeneic hematopoietic stem cell transplantation (HSCT) offers the potential to cure patients with an inherited bone marrow failure syndrome (IBMFS). However, the procedure involves the risk of treatment-rel...

R Peffault de Latour, C Peters, B Gibson, B Strahm… in Bone Marrow Transplantation (2015)

Article

Tandem high-dose chemotherapy strategy as first-line treatment of primary disseminated multifocal Ewing sarcomas in children, adolescents and young adults

The prognosis of primary disseminated multifocal metastatic Ewing’s sarcoma (PDMES) is poor even if a slight improvement has been achieved with high-dose alkylating agent-containing chemotherapy. To enhance tr...

S Loschi, C Dufour, O Oberlin, G Goma, D Valteau-Couanet… in Bone Marrow Transplantation (2015)

Article

Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015

This is the sixth special report that the European Society for Blood and Marrow Transplantation regularly publishes on the current practice and indications for haematopoietic SCT for haematological diseases, s...

A Sureda, P Bader, S Cesaro, P Dreger, R F Duarte, C Dufour… in Bone Marrow Transplantation (2015)

Article

Natural history of acute lymphoblastic leukemia in neurofibromatosis type 1 monozygotic twins

M Galbiati, A Lettieri, C Micalizzi, S Songia, C Morerio, A Biondi, C Dufour… in Leukemia (2013)

Article

Front-line immunosuppressive treatment of acquired aplastic anemia

In this article, front-line immunosuppressive therapy (IST) for acquired plastic anemia (AA) is illustrated and discussed. Also second-line and salvage options are briefly illustrated. First-line IST should co...

C Dufour, J Svahn, A Bacigalupo in Bone Marrow Transplantation (2013)

Article

Diagnosis of acquired aplastic anemia

Since the introduction of the concept of aplastic anemia (AA) by Paul Ehrlich in 1888 and despite the current better understanding of the underlying mechanisms involved in this disease, a clear delimitation am...

A Rovó, A Tichelli, C Dufour in Bone Marrow Transplantation (2013)

Article

Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model

B-acute lymphoblastic leukemia (B-ALL) represents the most common pediatric hematological tumor that derives from the aberrant proliferation of early B lymphocytes in the bone marrow. Although most of the B-AL...

S Canale, C Cocco, C Frasson, E Seganfreddo, E Di Carlo, E Ognio, C Sorrentino… in Leukemia (2011)

Article

Fanconi anaemia: new strategies

Fanconi anaemia (FA) is a rare genetic disease characterized by chromosomal instability, somatic abnormalities, marrow failure and cancer proness. The main cause of morbidity and mortality is bone marrow failu...

C Dufour, J Svahn in Bone Marrow Transplantation (2008)

Article

Are genotypes of glutathione S-transferase superfamily a risk factor for childhood acute lymphoblastic leukemia? Results of an Italian case–control study

S Pigullo, R Haupt, C Dufour, P Di Michele, M G Valsecchi, G Basso, C Rizzari… in Leukemia (2007)

Article

The polymorphisms −318C>T in the promoter and 49A>G in exon 1 of CTLA4 and the risk of aplastic anemia in a Caucasian population

Aplastic anemia (AA) is a rare disease with a major autoimmune pathogenetic component. CTLA4 is a T-lymphocyte surface molecule involved in the maintenance of immune tolerance. Some polymorphisms associated wi...

J Svahn, M Capasso, M Lanciotti, A Marrone, R Haupt… in Bone Marrow Transplantation (2005)

Article

Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements

NAD(P)H:quinone oxidoreductase 1 (NQO1) is a detoxification enzyme that protects cells against oxidative stress and toxic quinones. A polymorphism (C609T) in the gene produces in the heterozygous individuals (...

M Lanciotti, C Dufour, L Corral, P Di Michele, S Pigullo, G De Rossi, G Basso… in Leukemia (2005)