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    Article

    APOE2 enhances neuroprotection against Alzheimer’s disease through multiple molecular mechanisms

    The common APOE2 gene variant is neuroprotective against Alzheimer’s disease (AD) and reduces risk by nearly 50%. However, the mechanisms by which APOE2 confers neuroprotection are largely unknown. Here we sho...

    C Conejero-Goldberg, J J Gomar, T Bobes-Bascaran, T M Hyde… in Molecular Psychiatry (2014)

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    Article

    Molecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimer's disease as based on APOE genotype

    Alzheimer's disease (AD) is a neurodegenerative condition characterized histopathologically by neuritic plaques and neurofibrillary tangles. The objective of this transcriptional profiling study was to identif...

    C Conejero-Goldberg, T M Hyde, S Chen, U Dreses-Werringloer… in Molecular Psychiatry (2011)