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  1. Article

    Open Access

    Angle between DNA linker and nucleosome core particle regulates array compaction revealed by individual-particle cryo-electron tomography

    The conformational dynamics of nucleosome arrays generate a diverse spectrum of microscopic states, posing challenges to their structural determination. Leveraging cryogenic electron tomography (cryo-ET), we d...

    Meng Zhang, César Díaz-Celis, Jianfang Liu, **hui Tao in Nature Communications (2024)

  2. Article

    Open Access

    Fully Mechanically Controlled Automated Electron Microscopic Tomography

    Knowledge of three-dimensional (3D) structures of each individual particles of asymmetric and flexible proteins is essential in understanding those proteins’ functions; but their structures are difficult to de...

    **xin Liu, Hongchang Li, Lei Zhang, Matthew Rames, Meng Zhang in Scientific Reports (2016)