7 Result(s)
within
Byung-Mu Lee
Environmental Health
Occupational Medicine/Industrial Medicine
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Article
Repeated-dose toxicity and toxicokinetic study of isobutylparaben in rats subcutaneously treated for 13 weeks
Parabens have historically served as antimicrobial preservatives in a range of consumables such as food, beverages, medications, and personal care products due to their broad-spectrum antibacterial and antifun...
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Article
Correction to: Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats
A correction to this paper has been published: https://doi.org/10.1007/s00204-021-03054-8
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Article
Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats
Parabens are widely used preservatives in cosmetics and pharmaceutical products and are approved as food additives. These chemicals have been considered safe for many years. However, the literature classifies ...
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Article
Integration of transcriptomics, proteomics and metabolomics identifies biomarkers for pulmonary injury by polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in rats
Polyhexamethylene guanidine phosphate (PHMG-p) was used as a humidifier disinfectant in Korea. PHMG induced severe pulmonary fibrosis in Koreans. The objective of this study was to elucidate mechanism of pulmo...
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Article
Selenium-binding protein 1: a sensitive urinary biomarker to detect heavy metal-induced nephrotoxicity
Identifying novel biomarkers to detect nephrotoxicity is clinically important. Here, we attempted to identify new biomarkers for mercury-induced nephrotoxicity and compared their sensitivity to that of traditi...
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Article
Genetic and epigenetic cancer chemoprevention on molecular targets during multistage carcinogenesis
The main goal of cancer chemoprevention is to prevent or halt the progression of carcinogenesis with the administration of synthetic or natural compounds. Fundamental chemopreventive strategies include inhibit...
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Article
Evaluation of metabolomic profiling against renal toxicity in Sprague–Dawley rats treated with melamine and cyanuric acid
Melamine-induced renal toxicity is associated with crystal formation in the kidney following exposure to melamine and cyanuric acid. However, metabolomic profiling of intact kidney tissue after chronic intake ...
