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  1. Article

    Open Access

    Human in vitro modeling of adjuvant formulations demonstrates enhancement of immune responses to SARS-CoV-2 antigen

    Adjuvants can enhance vaccine immunogenicity, but their mechanism of action is often incompletely understood, hampering rapid applicability for pandemic vaccines. Herein, we characterized the cellular and mole...

    Simon Doss-Gollin, Sanya Thomas, Byron Brook, Kimia Abedi, Célia Lebas… in npj Vaccines (2023)

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    Article

    Newborn susceptibility to infection vs. disease depends on complex in vivo interactions of host and pathogen

    The burden of newborn infectious disease has long been recognized as the highest across the entire human life span. The precise underlying cause is unfortunately still far from clear. A substantial body of dat...

    Byron Brook, Danny Harbeson, Rym Ben-Othman… in Seminars in Immunopathology (2017)