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  1. Article

    Open Access

    The metabolic cost of inspiratory muscle training in mechanically ventilated patients in critical care

    Diaphragmatic dysfunction is well documented in patients receiving mechanical ventilation. Inspiratory muscle training (IMT) has been used to facilitate weaning by strengthening the inspiratory muscles, yet th...

    Timothy O. Jenkins, Vicky MacBean… in Intensive Care Medicine Experimental (2023)

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  2. Article

    Open Access

    Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom

    The trajectory of mechanically ventilated patients with coronavirus disease 2019 (COVID-19) is essential for clinical decisions, yet the focus so far has been on admission characteristics without consideration...

    Brijesh V. Patel, Shlomi Haar, Rhodri Handslip… in Intensive Care Medicine (2021)

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  3. Article

    New Consensus Definitions for Sepsis and Septic Shock: Implications for Treatment Strategies and Drug Development?

    Sepsis continues to escape a precise diagnostic definition. The most recent consensus definition, termed Sepsis-3, highlights the importance of the maladaptive and potentially life-threatening host response to...

    Michael Berry, Brijesh V. Patel, Stephen J. Brett in Drugs (2017)

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