5 Result(s)

Article

Correction: Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge

Amanda J. F. Tamman, Dora Koller, Sheila Nagamatsu… in Neuropsychopharmacology (2024)

Article

Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder

Suicide attempt (SA) risk is elevated in individuals with bipolar disorder (BD), and DNA methylation patterns may serve as possible biomarkers of SA. We conducted epigenome-wide association studies (EWAS) of b...

Salahudeen Mirza, Camila N. C. Lima… in Translational Psychiatry (2024)

Article

Modeling the longitudinal changes of ancestry diversity in the Million Veteran Program

The Million Veteran Program (MVP) participants represent 100 years of US history, including significant social and demographic changes over time. Our study assessed two aspects of the MVP: (i) longitudinal cha...

Frank R. Wendt, Gita A. Pathak, Jacqueline Vahey, Xuejun Qin, Dora Koller… in Human Genomics (2023)

Article

Sex differences in the polygenic architecture of hearing problems in adults

Hearing problems (HP) in adults are common and are associated with several comorbid conditions. Its prevalence increases with age, reflecting the cumulative effect of environmental factors and genetic predispo...

Flavio De Angelis, Oana A. Zeleznik, Frank R. Wendt, Gita A. Pathak… in Genome Medicine (2023)

Article

Denisovan and Neanderthal archaic introgression differentially impacted the genetics of complex traits in modern populations

Introgression from extinct Neanderthal and Denisovan human species has been shown to contribute to the genetic pool of modern human populations and their phenotypic spectrum. Evidence of how Neanderthal introg...

Dora Koller, Frank R. Wendt, Gita A. Pathak, Antonella De Lillo… in BMC Biology (2022)