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  1. Article

    Open Access

    Susceptibility gene identification and risk evaluation model construction by transcriptome-wide association analysis for salt sensitivity of blood pressure

    Salt sensitivity of blood pressure (SSBP) is an intermediate phenotype of hypertension and is a predictor of long-term cardiovascular events and death. However, the genetic structures of SSBP are uncertain, an...

    Han Qi, Yun-Yi **e, **ao-Jun Yang, Juan **a, Kuo Liu, Feng-Xu Zhang in BMC Genomics (2024)

  2. Article

    Open Access

    The role of macrophage polarization and cellular crosstalk in the pulmonary fibrotic microenvironment: a review

    Pulmonary fibrosis (PF) is a progressive interstitial inflammatory disease with a high mortality rate. Patients with PF commonly experience a chronic dry cough and progressive dyspnoea for years without effect...

    Bo-wen Zhou, Hua-man Liu, Fei Xu, **n-hua Jia in Cell Communication and Signaling (2024)

  3. Article

    Open Access

    Neutralizing IL-16 enhances the efficacy of targeting Aurora-A therapy in colorectal cancer with high lymphocyte infiltration through restoring anti-tumor immunity

    Cancer cells can evade immune elimination by activating immunosuppressive signaling pathways in the tumor microenvironment (TME). Targeting immunosuppressive signaling pathways to promote antitumor immunity ha...

    Shiang-Jie Yang, Sheng-Tsung Chang, Kung-Chao Chang, Bo-Wen Lin in Cell Death & Disease (2024)

  4. Article

    Open Access

    Identification of WUSCHEL-related homeobox gene and truncated small peptides in transformation efficiency improvement in Eucalyptus

    The WUSCHEL-related Homeobox (WOX) genes, which encode plant-specific homeobox (HB) transcription factors, play crucial roles in regulating plant growth and development. However, the functions of WOX genes are li...

    Zhuo-Ao Zhang, Mei-Ying Liu, Shu-Ning Ren, **ao Liu, Yue-Hao Gao in BMC Plant Biology (2023)

  5. Article

    Open Access

    The p53/ZEB1-PLD3 feedback loop regulates cell proliferation in breast cancer

    Breast cancer is the most prevalent cancer globally, endangering women’s physical and mental health. Phospholipase D3 (PLD3) belongs to the phosphodiesterase family (PLD). PLD3 is related to insulin-mediated p...

    Bo-Wen Liu, Ning Sun, Hui Lin, Xue-Jie Zhou, Hai-Yan Ma, **n Wang in Cell Death & Disease (2023)

  6. Article

    Open Access

    Author Correction: Genomic insights into biased allele loss and increased gene numbers after genome duplication in autotetraploid Cyclocarya paliurus

    Rui-Min Yu, Ning Zhang, Bo-Wen Zhang, Yu Liang, **ao-Xu Pang, Lei Cao in BMC Biology (2023)

  7. Article

    Open Access

    Genomic insights into biased allele loss and increased gene numbers after genome duplication in autotetraploid Cyclocarya paliurus

    Autopolyploidy is a valuable model for studying whole-genome duplication (WGD) without hybridization, yet little is known about the genomic structural and functional changes that occur in autopolyploids after ...

    Rui-Min Yu, Ning Zhang, Bo-Wen Zhang, Yu Liang, **ao-Xu Pang, Lei Cao in BMC Biology (2023)

  8. No Access

    Article

    Selenium Deficiency Leads to Reduced Skeletal Muscle Cell Differentiation by Oxidative Stress in Mice

    Selenium (Se) is one of the essential trace elements in animal organisms with good antioxidant and immune-enhancing abilities. In this study, we investigated the effect and mechanism of Se deficiency on skelet...

    Bo-wen Bao, Zibo Kang, Yu Zhang, Kan Li, Ran Xu in Biological Trace Element Research (2023)

  9. Article

    Correction: Global deletion of optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease

    Sing-Wai Wong, Bo-Wen Huang, **angxiang Hu, Eui Ho Kim in Cell Death & Differentiation (2023)

  10. Article

    Open Access

    Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis

    Erectile dysfunction (ED), as one of the most prevalent consequences in male diabetic patients, has a serious impact on men's physical and mental health, and the treatment effect of diabetic mellitus erectile ...

    Huan Feng, Qi Liu, Zhiyao Deng, Hao Li, Huajie Zhang in Stem Cell Research & Therapy (2022)

  11. Article

    Open Access

    TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma

    TAR DNA-Binding Protein 43 (TDP-43) has been well studied in neurodegenerative diseases, but its potential role in malignance is still unclear. Here, we demonstrate that TDP-43 contributes to the suppression o...

    Bo-wen Liu, **ang-yun Wang, **-ling Cao, Lu-lu Chen, Yi-lei Wang in Communications Biology (2022)

  12. Article

    Open Access

    The resistance of peanut to soil-borne pathogens improved by rhizosphere probiotics under calcium treatment

    Peanut (Arachis hypogaea L.) is an important oil and economic crop. Calcium modulates plants in response to abiotic stresses and improves plant resistance to pathogens. Enrichment of beneficial microorganisms in ...

    Wei Zhang, Bo-wen Zhang, Jie-fu Deng, Lin Li, Tu-yong Yi, Yan-yun Hong in BMC Microbiology (2021)

  13. Article

    Open Access

    The nuclear bodies formed by histone demethylase KDM7A

    Hui Ming, Qianfeng Wang, Yuwen Zhang, Luzhang Ji, Lu Cheng, **angru Huo in Protein & Cell (2021)

  14. Article

    Correction: Global deletion of optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    Sing-Wai Wong, Bo-Wen Huang, **angxiang Hu, Eui Ho Kim in Cell Death & Differentiation (2021)

  15. No Access

    Article

    Genome-wide identification and expression analysis of the CLC superfamily genes in tea plants (Camellia sinensis)

    The voltage-gated chloride channel (CLC) superfamily is one of the most important anion channels that is widely distributed in bacteria and plants. CLC is involved in transporting various anions such as chlori...

    Anqi **ng, Yuanchun Ma, Zichen Wu, Shouhua Nong in Functional & Integrative Genomics (2020)

  16. No Access

    Article

    Aluminum relieves fluoride stress through stimulation of organic acid production in Camellia sinensis

    Tea plants (Camellia sinensis O. Kuntze) can hyperaccumulate fluoride (F) in leaves. Although, aluminum (Al) can alleviate F toxicity in C. sinensis, the mechanisms driving this process remain unclear. Here, we m...

    Junting Pan, Dongqin Li, Jiaojiao Zhu in Physiology and Molecular Biology of Plants (2020)

  17. No Access

    Article

    Characteristics of soil nutrients, heavy metals and tea quality in different intercrop** patterns

    Intercrop** is an important agroforestry practice that can not only increase biodiversity, improve microenvironment and resource utilization, but also improve crop yield and quality. In this paper, the soil ...

    Bo Wen, **aolei Zhang, Shuang Ren, Yu Duan, Yanyuan Zhang in Agroforestry Systems (2020)

  18. No Access

    Article

    Screening of Biomarkers Related to Ovarian Maturation and Spawning in Blunt Snout Bream (Megalobrama amblycephala) Based on Metabolomics and Transcriptomics

    In fish breeding practices, gamete maturity of females is vital to reproductive success. For some species, it is possible to estimate the female maturation status based on abdomen observation, but quite diffic...

    Shaokui Yi, Li-Fang Liu, Lai-Fang Zhou, Bo-Wen Zhao, Wei-Min Wang in Marine Biotechnology (2020)

  19. No Access

    Article

    Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget’s disease

    Genome-wide association studies (GWAS) have identified Optineurin (OPTN) as genetically linked to Paget’s disease of the bone (PDB), a chronic debilitating bone remodeling disorder characterized by localized area...

    Sing-Wai Wong, Bo-Wen Huang, **angxiang Hu, Eui Ho Kim in Cell Death & Differentiation (2020)

  20. No Access

    Article

    Effects of soybean–tea intercrop** on soil-available nutrients and tea quality

    Plant intercrop** is increasing in popularity, is conducive to plant growth and development and can improve plant quality and yield. In this study, we intercropped tea (Camellia sinensis) cv. ‘Su cha zao’ and s...

    Yu Duan, Jiazhi Shen, **aolei Zhang, Bo Wen, Yuanchun Ma in Acta Physiologiae Plantarum (2019)

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