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Article

PEG-conjugated PAMAM Dendrimers Mediate Efficient Intramuscular Gene Expression

Generations 5 and 6 (G5 and G6) poly(amidoamine) (PAMAM) dendrimers have been shown to be highly efficient nonviral carriers in in vitro gene delivery. However, their high toxicity and unsatisfied in vivo efficac...

Rong Qi, Yu Gao, Yin Tang, Rui-Rui He, Tao-Le Liu, Yun He, Sheng Sun… in The AAPS Journal (2009)