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Article
Open AccessNitrogen addition has divergent effects on phosphorus fractions in four types of soils
Globally increasing atmospheric nitrogen (N) deposition has altered soil phosphorus (P) transformations and availability, and thereby influenced structure and function of terrestrial ecosystems. Edaphic charac...
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Article
Consistent epistemic planning for multiagent deep reinforcement learning
Multiagent cooperation in a partially observable environment without communication is difficult because of the uncertainty of agents. Traditional multiagent deep reinforcement learning (MADRL) algorithms fail ...
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Article
Open AccessBacterial interactome disturbance in chronic obstructive pulmonary disease clinical stability and exacerbations
Our understanding of airway dysbiosis in chronic obstructive pulmonary disease (COPD) remains incomplete, which may be improved by unraveling the complexity in microbial interactome.
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Article
Evaluating variations in the barriers to colorectal cancer screening associated with telehealth use in rural U.S. Pacific Northwest
The incidence and mortality rates of colorectal cancer (CRC) remain consistently high in rural populations. Telehealth can improve screening uptake by overcoming individual and environmental disadvantages in r...
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Article
Open AccessDeep learning model for personalized prediction of positive MRSA culture using time-series electronic health records
Methicillin-resistant Staphylococcus aureus (MRSA) poses significant morbidity and mortality in hospitals. Rapid, accurate risk stratification of MRSA is crucial for optimizing antibiotic therapy. Our study intro...
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Article
Lacticaseibacillus paracasei CCFM1222 Ameliorated the Intestinal Barrier and Regulated Gut Microbiota in Mice with Dextran Sulfate Sodium-Induced Colitis
Lacticaseibacillus paracasei has been regarded as a probiotic bacterium because of its role in anti-inflammatory properties and maintenance of intestinal barrier permeability. Here, we explored the anticolitic ef...
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Article
Preparing the photo- and heat-stable PGMA/CdTe quantum dot composite films and exploring devices for LED-display poster design
Inorganic quantum dots (QDs) are used in color displays because of wide photo-absorption and controllable photoluminescence (PL) colors, but their PL stability may be low due to surface defects. To overcome it...
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Article
Intestinal Microbiomics and Metabolomics Insights into the Hepatoprotective Effects of Lactobacillus paracasei CCFM1222 Against the Acute Liver Injury in Mice
In recent years, acute liver injury (ALI) has received wide-range attention in the world due to its relatively high morbidity and mortality. This study aimed to explore the hepatoprotective effect of Lactobacillu...
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Article
Population genomics of Lacticaseibacillus paracasei: pan-genome, integrated prophage, antibiotic resistance, and carbohydrate utilization
Lacticaseibacillus paracasei has beneficial effects on human health and holds promising potential as a probiotic for use in the development of functional foods, especially dairy products. This species can adapt t...
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Article
Open AccessSmurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma
Sonic hedgehog (Shh)-group medulloblastoma (MB) (Shh-MB) encompasses a clinically and molecularly distinct group of cancers originating from the develo** nervous system with aberrant high Shh signaling as a ...
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Article
Lactobacillus reuteri CCFM1175 and Lactobacillus paracasei CCFM1176 Could Prevent Capsaicin-Induced Ileal and Colonic Injuries
Capsaicin (CAP) is usually reported to have many biological activities. However, a large intake of CAP may cause heartburn, gastrointestinal pain, and diarrhea. In this study, mice were gavaged with nine lacti...
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Article
Potential Probiotic Properties of Blautia producta Against Lipopolysaccharide-Induced Acute Liver Injury
Blautia is a genus of anaerobic microbe extensively present in the intestine and feces of mammals. This study aims to investigate the influence of Blautia producta to prevent lipopolysaccharide (LPS)-induced acut...
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Article
Efficient production and biochemical characterization of a thermostable carboxypeptidase from Bacillus megaterium and its application on flavor improvement of soy isolate protein hydrolysates
A carboxypeptidase M32 (CPM32) gene (cpm32) from Bacillus megaterium was cloned. CPM32 exhibited the highest sequence similarity of 79.3% with the same from Priestia veravalensis. CPM32 was fused with the signal ...
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Article
Notably decreased dielectric loss of high dielectric constant P(VDF-TrFE)/CuBTC MOF composites through adding silica powder
High dielectric constant (high-k) for energy storage is obtained in composites bearing polar polymer matrix and polar metal–organic-framework (MOF) filler via electrostatic interaction between polymer and MOF. Ne...
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Article
Key mitigation regions and strategies for CO2 emission reduction in China based on STIRPAT and ARIMA models
China is facing increasing pressure to reduce CO2 emissions from energy consumption. Given this issue, understanding the characteristics, influencing factors, and trends can provide adequate information for decis...
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Article
2D phosphorus carbide as promising anode materials for Na/K-ion batteries from first-principles study
First-principles calculations based on density functional theory were used to investigate the electrochemical performance of monolayer γ-PC for Na- and K-ion batteries. Molecular dynamics simulations indicate ...
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Article
Open AccessEfficacy and safety of Tanreqing oral liquid in treatment of acute bronchitis: study protocol for a randomized controlled trial
Approximately 5% of adults have an episode of acute bronchitis each year, accounting for more than 10 million medical visits yearly. The primary goal of treatment is reduction of symptoms. Currently, available...
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Article
Tailored Messages About Research Participation: Using an Interactive Information Aid to Improve Study Recruitment
After a diagnosis of cancer (or other serious disease), patients may be asked to consider joining a clinical trial. Because most people are unfamiliar with the scientific concepts that are necessary to the pro...
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Article
Open AccessSatb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1
Dopaminergic (DA) neurons in the arcuate nucleus (ARC) of the hypothalamus play essential roles in the secretion of prolactin and the regulation of energy homeostasis. However, the gene regulatory network resp...
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Article
Correction to: Preoperative classification of primary and metastatic liver cancer via machine learning-based ultrasound radiomics
A Correction to this paper has been published: https://doi.org/10.1007/s00330-021-07704-4
