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Open AccessP2X7 receptor: a potential target for treating comorbid anxiety and depression
In clinical practice, depression and anxiety frequently coexist, and they are both comorbid with somatic diseases. The P2X7R is an adenosine 5’-triphosphate (ATP)-gated non-selective cation channel that is wid...
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Open AccessP2Y12 receptor gene polymorphisms are associated with epilepsy
The basic research indicated that microglial P2Y12 receptors (P2Y12Rs) are involved in the pathophysiology of epilepsy through regulated microglial-neuronal interactions, aberrant neurogenesis, or immature neuron...