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  1. Article

    Open Access

    P2X7 receptor: a potential target for treating comorbid anxiety and depression

    In clinical practice, depression and anxiety frequently coexist, and they are both comorbid with somatic diseases. The P2X7R is an adenosine 5’-triphosphate (ATP)-gated non-selective cation channel that is wid...

    Jun Liu, Ting-Ting Liu, Lan Mou, Yuwen Zhang, **ang Chen, Qi Wang in Purinergic Signalling (2024)

  2. Article

    Open Access

    P2Y12 receptor gene polymorphisms are associated with epilepsy

    The basic research indicated that microglial P2Y12 receptors (P2Y12Rs) are involved in the pathophysiology of epilepsy through regulated microglial-neuronal interactions, aberrant neurogenesis, or immature neuron...

    Qi Wang, Nan-Rui Shi, Peng Lv, Juan Liu, Ji-Zhou Zhang in Purinergic Signalling (2023)