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Advances in Structure Determination of G Protein-Coupled Receptors by SFX
G protein-coupled receptors (GPCRs) constitute the largest superfamily of membrane proteins, members of which are involved in regulation of critical sensory and physiological processes in the human body. High-...
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Article
Open AccessThe description of protein internal motions aids selection of ligand binding poses by the INPHARMA method
Protein internal motions influence observables of NMR experiments. The effect of internal motions occurring at the sub-nanosecond timescale can be described by NMR order parameters. Here, we report that the us...