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Article
Open AccessIntegrative and comparative genomics analysis of early hepatocellular carcinoma differentiated from liver regeneration in young and old
Hepatocellular carcinoma (HCC) is the third-leading cause of cancer-related deaths worldwide. It is often diagnosed at an advanced stage, and hence typically has a poor prognosis. To identify distinct molecula...
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Article
Open AccessThe growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation
Although a high frequency of androgen receptor (AR) expression in human breast cancers has been described, exploiting this knowledge for therapy has been challenging. This is in part because androgens can eith...
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Article
The breast is yet to come: current and future utility of circulating tumour DNA in breast cancer
Advances in genomic strategies and the development of targeted therapies have enabled precision medicine to revolutionise the field of oncology. Precision medicine uses patient-specific genetic and molecular i...