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393 Result(s)
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Article
Haptoglobin DNA polymorphism in subterranean mole rats of the Spalax ehrenbergi superspecies in Israel
We analyzed the genetic diversity and environmental correlates of the haptoglobin (Hp) gene by RFLP analysis of 121 subterranean mole rats, comprising 13 populations belonging to the 4 chromosomal species (2n ...
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Population genetics of the moss Plagiothecium undulatum (Hedw.) Schimp. I. Inheritance of allozymes
Twenty-one allozyme loci were assayed in a subpopulation of the dioecious moss Plagiothecium undulatum. Six loci were polymorphic and could be used to demonstrate the different expression of allozymes at the hapl...
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Period-homologous sequence polymorphisms in subterranean mammals of the Spalax ehrenbergi superspecies in Israel
Restriction fragment length polymorphism (RFLPs) of the mouse period-homologous sequence were studied in 13 populations of the four chromosomal species (2n = 52, 54, 58 and 60) of the mole rat, Spalax ehrenbergi ...
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Recent studies of avian sex ratios
Sex allocation theory, and its success in predicting sex ratios in such taxa as parasitoid wasps, is often cited as one of the crowning achievements of theoretical evolutionary biology. Its success in some ver...
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Correction: Mutations in GDI1 are responsible for X-linked non-specific mental retardation
Nature Genet. 19, 134–139 (1998).
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Genetic architecture of fitness and nonfitness traits: empirical patterns and development of ideas
Comparative studies of the genetic architecture of different types of traits were initially prompted by the expectation that traits under strong directional selection (fitness traits) should have lower levels ...
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Analysis of gene expression data: clustering and beyond
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Analyzing functional genomic differences yields oncogenes and chromosomal breakpoints in ALL and AML
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Statistical benchmarking and class discovery in gene expression data
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Retroviral proteases
The proteases of retroviruses, such as leukemia viruses, immunodeficiency viruses (including the human immunodeficiency virus, HIV), infectious anemia viruses, and mammary tumor viruses, form a family with the...
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Cancer and programmed cell death
A report on the 15th Lorne Cancer Conference, Lorne, Australia, 13-16 February 2003.
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Fanconi anemia in Tunisia: high prevalence of group A and identification of new FANCA mutations
Fanconi anemia (FA) is a rare autosomal recessive disease characterized by progressive pancytopenia, congenital malformations, and predisposition to acute myeloid leukemia. Fanconi anemia is genetically hetero...
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Recent segmental and gene duplications in the mouse genome
The high quality of the mouse genome draft sequence and its associated annotations are an invaluable biological resource. Identifying recent duplications in the mouse genome, especially in regions containing g...
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Root genomics: towards digital in situ hybridization
Separation of cell types and developmental stages in the Arabidopsis root and subsequent expression profiling have yielded a valuable dataset that can be used to select candidate genes for detailed study and to s...
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Open AccessA 4q35.2 subtelomeric deletion identified in a screen of patients with co-morbid psychiatric illness and mental retardation
Cryptic structural abnormalities within the subtelomeric regions of chromosomes have been the focus of much recent research because of their discovery in a percentage of people with mental retardation (UK term...
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Open AccessA first-draft human protein-interaction map
Protein-interaction maps are powerful tools for suggesting the cellular functions of genes. Although large-scale protein-interaction maps have been generated for several invertebrate species, projects of a sim...
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Open AccessBioconductor: open software development for computational biology and bioinformatics
The Bioconductor project is an initiative for the collaborative creation of extensible software for computational biology and bioinformatics. The goals of the project include: fostering collaborative developme...
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Open AccessAlternative splicing of mouse transcription factors affects their DNA-binding domain architecture and is tissue specific
Analyzing proteins in the context of all available genome and transcript sequence data has the potential to reveal functional properties not accessible through protein sequence analysis alone. To analyze the i...
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Erratum: Mitochondrial proapoptotic ARTS protein is lost in the majority of acute lymphoblastic leukemia patients
Correction to: Oncogene (2004) 23, 5468–5475. doi:10.1038/sj.onc.1207725 Due to a typesetting error, Figure 6 appeared in monotone rather than colour. The correct version of the figure is given below.
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Open AccessCatechol-O-Methyltransferase (COMT) Val 108/158 Metpolymorphism does not modulate executive function in children with ADHD
An association has been observed between the catechol-O-methyltransferase (COMT) gene, the predominant means of catecholamine catabolism within the prefrontal cortex (PFC), and neuropsychological task performance...