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Chapter
Continuous Optimal CPP Based on Minute-by-Minute Monitoring Data: A Study of a Pediatric Population
This paper describes the use of minute-by-minute monitoring data to determine continuous optimal cerebral perfusion pressure (CPP) recommendations based on the autoregulatory status of pediatric patients with ...
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Chapter and Conference Paper
Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury
Objective: The aim of this study is to assess visually the impact of duration and intensity of cerebrovascular autoregulation insults on 6-month neurological outcome in severe traumatic brain injury.
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Chapter and Conference Paper
Cerebral Perfusion Pressure Variability Between Patients and Between Centres
Introduction: The aim of this analysis was to investigate to what extent median cerebral perfusion pressure (CPP) differs between severe traumatic brain injury (TBI) patients and between centres, and whether the...
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Chapter
An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury
Introduction: Monitoring of cerebral autoregulation (CA) in patients with a traumatic brain injury (TBI) can provide an individual ‘optimal’ cerebral perfusion pressure (CPP) target (CPPopt) at which CA is best ...