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Article
Open AccessEarly surgery versus conservative treatment in patients with traumatic intracerebral hematoma: a CENTER-TBI study
Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on the STITCH(Trauma) trial. This study is aimed at comparing the effectiveness of early surgery to co...
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Article
Long-term outcomes after traumatic brain injury in elderly patients on antithrombotic therapy
Elderly patients receiving antithrombotic treatment have a significantly higher risk of develo** an intracranial hemorrhage when suffering traumatic brain injury (TBI), potentially contributing to higher mor...
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Article
Profound prospective assessment of radiological and functional outcome 6 months after TBI in elderly
Recovery after traumatic brain injury (TBI) in older adults is usually affected by the presence of comorbidities, leading to more severe sequelae in this age group than in younger patients. However, there are ...
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Article
Rehabilitation to improve outcomes of lumbar fusion surgery: a systematic review with meta-analysis
To evaluate the effectiveness of rehabilitation strategies on disability, pain, pain-related fear, and return-to-work in patients undergoing lumbar fusion surgery for degenerative conditions or adult isthmic s...
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Article
Traumatic brain injury in the elderly population: a 20-year experience in a tertiary neurosurgery center in Belgium
Traumatic brain injury (TBI) rates in the elderly population are rapidly increasing worldwide. However, there are no clinical guidelines for the treatment of elderly TBI to date. This study aims at describing ...
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Article
Association of Dose of Intracranial Hypertension with Outcome in Subarachnoid Hemorrhage
In patients with aneurysmal subarachnoid hemorrhage (aSAH) the burden of intracranial pressure (ICP) and its contribution to outcomes remains unclear. In this multicenter study, the independent association bet...
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Article
International comparative study of low back pain care pathways and analysis of key interventions
Low back pain (LBP) is a major public health problem worldwide. Significant practice variation exists despite guidelines, including strong interventionist focus by some practitioners. Translation of guidelines...
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Chapter
An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury
Introduction: Monitoring of cerebral autoregulation (CA) in patients with a traumatic brain injury (TBI) can provide an individual ‘optimal’ cerebral perfusion pressure (CPP) target (CPPopt) at which CA is best ...
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Article
How good are the outcomes of instrumented debulking operations for symptomatic spinal metastases and how long do they stand? A subgroup analysis in the global spine tumor study group database
The benefits of surgery for symptomatic spinal metastases have been demonstrated, largely based on series of patients undergoing debulking and instrumentation operations. However, as cancer treatments improve ...
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Article
Postoperative bracing after lumbar surgery: a survey amongst spinal surgeons in Belgium
Bracing is frequently prescribed following lumbar surgery for degenerative conditions. However, previous studies failed to demonstrate the advantage of postoperative lumbar bracing in both short- and long-term...
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Chapter and Conference Paper
Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury
Objective: The aim of this study is to assess visually the impact of duration and intensity of cerebrovascular autoregulation insults on 6-month neurological outcome in severe traumatic brain injury.
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Chapter and Conference Paper
Cerebral Perfusion Pressure Variability Between Patients and Between Centres
Introduction: The aim of this analysis was to investigate to what extent median cerebral perfusion pressure (CPP) differs between severe traumatic brain injury (TBI) patients and between centres, and whether the...
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Chapter
Continuous Optimal CPP Based on Minute-by-Minute Monitoring Data: A Study of a Pediatric Population
This paper describes the use of minute-by-minute monitoring data to determine continuous optimal cerebral perfusion pressure (CPP) recommendations based on the autoregulatory status of pediatric patients with ...
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Article
Observation of Autoregulation Indices During Ventricular CSF Drainage After Aneurysmal Subarachnoid Hemorrhage: A Pilot Study
Cerebral autoregulation is increasingly recognized as a factor that requires evaluation when managing poor grade aneurysmal subarachnoïdal hemorrhage (aSAH) patients. In this single center pilot study, we inve...
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Article
Qualitative and quantitative assessment of degeneration of cervical intervertebral discs and facet joints
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Chapter and Conference Paper
Study of perfusion in and around cerebral contusions by means of computed tomography
Background Several authors have found low absolute values of cerebral blood flow (CBF) in both contusion core and pericontusional parenchyma of head-injured patients by means of Xenon Com...