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  1. Article

    Open Access

    Early management of adult traumatic spinal cord injury in patients with polytrauma: a consensus and clinical recommendations jointly developed by the World Society of Emergency Surgery (WSES) & the European Association of Neurosurgical Societies (EANS)

    The early management of polytrauma patients with traumatic spinal cord injury (tSCI) is a major challenge. Sparse data is available to provide optimal care in this scenario and worldwide variability in clinica...

    Edoardo Picetti, Andreas K. Demetriades in World Journal of Emergency Surgery (2024)

  2. Article

    Open Access

    Early surgery versus conservative treatment in patients with traumatic intracerebral hematoma: a CENTER-TBI study

    Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on the STITCH(Trauma) trial. This study is aimed at comparing the effectiveness of early surgery to co...

    Inge A. M. van Erp, Thomas A. van Essen, Hester Lingsma in Acta Neurochirurgica (2023)

  3. No Access

    Article

    Long-term outcomes after traumatic brain injury in elderly patients on antithrombotic therapy

    Elderly patients receiving antithrombotic treatment have a significantly higher risk of develo** an intracranial hemorrhage when suffering traumatic brain injury (TBI), potentially contributing to higher mor...

    Rebeca Alejandra Gavrila Laic, Peter Verhamme, Jos Vander Sloten in Acta Neurochirurgica (2023)

  4. No Access

    Article

    Profound prospective assessment of radiological and functional outcome 6 months after TBI in elderly

    Recovery after traumatic brain injury (TBI) in older adults is usually affected by the presence of comorbidities, leading to more severe sequelae in this age group than in younger patients. However, there are ...

    Rebeca Alejandra Gavrila Laic, Jan Verheyden, Dominike Bruyninckx in Acta Neurochirurgica (2023)

  5. Article

    Open Access

    Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion

    Julie Messiaen, Annelies Claeys, Aniket Shetty, Lien Spans in Acta Neuropathologica (2022)

  6. No Access

    Article

    Rehabilitation to improve outcomes of lumbar fusion surgery: a systematic review with meta-analysis

    To evaluate the effectiveness of rehabilitation strategies on disability, pain, pain-related fear, and return-to-work in patients undergoing lumbar fusion surgery for degenerative conditions or adult isthmic s...

    Liedewij Bogaert, Tinne Thys, Bart Depreitere, Wim Dankaerts in European Spine Journal (2022)

  7. No Access

    Article

    Traumatic brain injury in the elderly population: a 20-year experience in a tertiary neurosurgery center in Belgium

    Traumatic brain injury (TBI) rates in the elderly population are rapidly increasing worldwide. However, there are no clinical guidelines for the treatment of elderly TBI to date. This study aims at describing ...

    Rebeca Alejandra Gavrila Laic, Jos Vander Sloten, Bart Depreitere in Acta Neurochirurgica (2022)

  8. Article

    Open Access

    Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (RESET-ASDH trial): study protocol for a pragmatic randomized controlled trial with multicenter parallel group design

    The rapidly increasing number of elderly (≥ 65 years old) with TBI is accompanied by substantial medical and economic consequences. An ASDH is the most common injury in elderly with TBI and the surgical versus...

    Ranjit D. Singh, Jeroen T. J. M. van Dijck, Thomas A. van Essen in Trials (2022)

  9. Article

    Open Access

    Generalization of fear of movement-related pain and avoidance behavior as predictors of work resumption after back surgery: a study protocol for a prospective study (WABS)

    Previous studies indicated that about 20% of the individuals undergoing back surgery are unable to return to work 3 months to 1 year after surgery. The specific factors that predict individual trajectories in ...

    Rini Masuy, Lotte Bamelis, Katleen Bogaerts, Bart Depreitere in BMC Psychology (2022)

  10. No Access

    Article

    Association of Dose of Intracranial Hypertension with Outcome in Subarachnoid Hemorrhage

    In patients with aneurysmal subarachnoid hemorrhage (aSAH) the burden of intracranial pressure (ICP) and its contribution to outcomes remains unclear. In this multicenter study, the independent association bet...

    Giorgia Carra, Francesca Elli, Bogdan Ianosi, Marine Flechet in Neurocritical Care (2021)

  11. No Access

    Article

    International comparative study of low back pain care pathways and analysis of key interventions

    Low back pain (LBP) is a major public health problem worldwide. Significant practice variation exists despite guidelines, including strong interventionist focus by some practitioners. Translation of guidelines...

    Ellen Coeckelberghs, Hilde Verbeke, Anja Desomer in European Spine Journal (2021)

  12. No Access

    Chapter

    An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury

    Introduction: Monitoring of cerebral autoregulation (CA) in patients with a traumatic brain injury (TBI) can provide an individual ‘optimal’ cerebral perfusion pressure (CPP) target (CPPopt) at which CA is best ...

    Jeanette Tas, Erta Beqiri, C. R. van Kaam in Intracranial Pressure and Neuromonitoring … (2021)

  13. No Access

    Article

    Prediction model for intracranial hypertension demonstrates robust performance during external validation on the CENTER-TBI dataset

    Giorgia Carra, Fabian Güiza, Bart Depreitere, Geert Meyfroidt in Intensive Care Medicine (2021)

  14. No Access

    Article

    Collagen fibre orientation in human bridging veins

    Bridging veins (BVs) drain the blood from the cerebral cortex into dural sinuses. BVs have one end attached to the brain and the other to the superior sagittal sinus (SSS), which is attached to the skull. Rela...

    Markos Kapeliotis in Biomechanics and Modeling in Mechanobiology (2020)

  15. No Access

    Article

    How good are the outcomes of instrumented debulking operations for symptomatic spinal metastases and how long do they stand? A subgroup analysis in the global spine tumor study group database

    The benefits of surgery for symptomatic spinal metastases have been demonstrated, largely based on series of patients undergoing debulking and instrumentation operations. However, as cancer treatments improve ...

    Bart Depreitere, Federico Ricciardi, Mark Arts, Laurent Balabaud in Acta Neurochirurgica (2020)

  16. Article

    Open Access

    How I monitor cerebral autoregulation

    Samuel P. Klein, Bart Depreitere, Geert Meyfroidt in Critical Care (2019)

  17. No Access

    Article

    Postoperative bracing after lumbar surgery: a survey amongst spinal surgeons in Belgium

    Bracing is frequently prescribed following lumbar surgery for degenerative conditions. However, previous studies failed to demonstrate the advantage of postoperative lumbar bracing in both short- and long-term...

    Liedewij Bogaert, Peter Van Wambeke, Tinne Thys in European Spine Journal (2019)

  18. No Access

    Chapter and Conference Paper

    Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury

    Objective:  The aim of this study is to assess visually the impact of duration and intensity of cerebrovascular autoregulation insults on 6-month neurological outcome in severe traumatic brain injury.

    Marine Flechet, Geert Meyfroidt, Ian Piper in Intracranial Pressure & Neuromonitoring XVI (2018)

  19. No Access

    Chapter and Conference Paper

    Cerebral Perfusion Pressure Variability Between Patients and Between Centres

    Introduction: The aim of this analysis was to investigate to what extent median cerebral perfusion pressure (CPP) differs between severe traumatic brain injury (TBI) patients and between centres, and whether the...

    Bart Depreitere, Fabian Güiza, Ian Piper in Intracranial Pressure & Neuromonitoring XVI (2018)

  20. Article

    Open Access

    Antibody profiling identifies novel antigenic targets in spinal cord injury patients

    Recent evidence implicates antibody responses as pivotal damaging factors in spinal cord injury (SCI)-induced neuroinflammation. To date, only a limited number of the antibody targets have been uncovered, and ...

    Ilse Palmers, Elke Ydens, Eric Put, Bart Depreitere in Journal of Neuroinflammation (2016)

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