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Chapter and Conference Paper
Study of perfusion in and around cerebral contusions by means of computed tomography
Background Several authors have found low absolute values of cerebral blood flow (CBF) in both contusion core and pericontusional parenchyma of head-injured patients by means of Xenon Com...
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Article
Observation of Autoregulation Indices During Ventricular CSF Drainage After Aneurysmal Subarachnoid Hemorrhage: A Pilot Study
Cerebral autoregulation is increasingly recognized as a factor that requires evaluation when managing poor grade aneurysmal subarachnoïdal hemorrhage (aSAH) patients. In this single center pilot study, we inve...
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Article
How good are the outcomes of instrumented debulking operations for symptomatic spinal metastases and how long do they stand? A subgroup analysis in the global spine tumor study group database
The benefits of surgery for symptomatic spinal metastases have been demonstrated, largely based on series of patients undergoing debulking and instrumentation operations. However, as cancer treatments improve ...
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Chapter
An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury
Introduction: Monitoring of cerebral autoregulation (CA) in patients with a traumatic brain injury (TBI) can provide an individual ‘optimal’ cerebral perfusion pressure (CPP) target (CPPopt) at which CA is best ...
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Article
Association of Dose of Intracranial Hypertension with Outcome in Subarachnoid Hemorrhage
In patients with aneurysmal subarachnoid hemorrhage (aSAH) the burden of intracranial pressure (ICP) and its contribution to outcomes remains unclear. In this multicenter study, the independent association bet...
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Article
Traumatic brain injury in the elderly population: a 20-year experience in a tertiary neurosurgery center in Belgium
Traumatic brain injury (TBI) rates in the elderly population are rapidly increasing worldwide. However, there are no clinical guidelines for the treatment of elderly TBI to date. This study aims at describing ...
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Article
Profound prospective assessment of radiological and functional outcome 6 months after TBI in elderly
Recovery after traumatic brain injury (TBI) in older adults is usually affected by the presence of comorbidities, leading to more severe sequelae in this age group than in younger patients. However, there are ...
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Article
Long-term outcomes after traumatic brain injury in elderly patients on antithrombotic therapy
Elderly patients receiving antithrombotic treatment have a significantly higher risk of develo** an intracranial hemorrhage when suffering traumatic brain injury (TBI), potentially contributing to higher mor...
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Article
Open AccessEarly surgery versus conservative treatment in patients with traumatic intracerebral hematoma: a CENTER-TBI study
Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on the STITCH(Trauma) trial. This study is aimed at comparing the effectiveness of early surgery to co...