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Chapter and Conference Paper
Study of perfusion in and around cerebral contusions by means of computed tomography
Background Several authors have found low absolute values of cerebral blood flow (CBF) in both contusion core and pericontusional parenchyma of head-injured patients by means of Xenon Com...
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Article
Observation of Autoregulation Indices During Ventricular CSF Drainage After Aneurysmal Subarachnoid Hemorrhage: A Pilot Study
Cerebral autoregulation is increasingly recognized as a factor that requires evaluation when managing poor grade aneurysmal subarachnoïdal hemorrhage (aSAH) patients. In this single center pilot study, we inve...
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Chapter
Continuous Optimal CPP Based on Minute-by-Minute Monitoring Data: A Study of a Pediatric Population
This paper describes the use of minute-by-minute monitoring data to determine continuous optimal cerebral perfusion pressure (CPP) recommendations based on the autoregulatory status of pediatric patients with ...
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Chapter and Conference Paper
Visualizing Cerebrovascular Autoregulation Insults and Their Association with Outcome in Adult and Paediatric Traumatic Brain Injury
Objective: The aim of this study is to assess visually the impact of duration and intensity of cerebrovascular autoregulation insults on 6-month neurological outcome in severe traumatic brain injury.
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Chapter and Conference Paper
Cerebral Perfusion Pressure Variability Between Patients and Between Centres
Introduction: The aim of this analysis was to investigate to what extent median cerebral perfusion pressure (CPP) differs between severe traumatic brain injury (TBI) patients and between centres, and whether the...
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Chapter
An Update on the COGiTATE Phase II Study: Feasibility and Safety of Targeting an Optimal Cerebral Perfusion Pressure as a Patient-Tailored Therapy in Severe Traumatic Brain Injury
Introduction: Monitoring of cerebral autoregulation (CA) in patients with a traumatic brain injury (TBI) can provide an individual ‘optimal’ cerebral perfusion pressure (CPP) target (CPPopt) at which CA is best ...
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Article
Association of Dose of Intracranial Hypertension with Outcome in Subarachnoid Hemorrhage
In patients with aneurysmal subarachnoid hemorrhage (aSAH) the burden of intracranial pressure (ICP) and its contribution to outcomes remains unclear. In this multicenter study, the independent association bet...