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Retrospective studies and quantitative proteomics reveal that abnormal expression of blood pressure, blood lipids, and coagulation related proteins is associated with hypospadias

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  1. Article

    Open Access

    Plasma metabolomic profile in orthostatic intolerance children with high levels of plasma homocysteine

    Orthostatic intolerance, which includes vasovagal syncope and postural orthostatic tachycardia syndrome, is common in children and adolescents. Elevated plasma homocysteine levels might participate in the path...

    Yaqi Li, Baoling Bai, Hui Wang, Haojie Wu, Yanjun Deng… in Italian Journal of Pediatrics (2024)

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  2. Article

    Open Access

    High Homocysteine-Thiolactone Leads to Reduced MENIN Protein Expression and an Impaired DNA Damage Response: Implications for Neural Tube Defects

    DNA damage is associated with hyperhomocysteinemia (HHcy) and neural tube defects (NTDs). Additionally, HHcy is a risk factor for NTDs. Therefore, this study examined whether DNA damage is involved in HHcy-ind...

    Baoling Bai, Chunlei Wan, Zonghui **ao, Dan Li, Lingyun Liu… in Molecular Neurobiology (2024)

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  3. Article

    Open Access

    Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects

    Neural tube defects (NTDs) are serious congenital malformations. Excessive maternal homocysteine (Hcy) increases the risk of NTDs, while its mechanism remains elusive. Here we report the role of histone homocy...

    Qin Zhang, Baoling Bai, **nyu Mei, Chunlei Wan, Haiyan Cao, Dan Li… in Nature Communications (2018)

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