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  1. Article

    Open Access

    High Homocysteine-Thiolactone Leads to Reduced MENIN Protein Expression and an Impaired DNA Damage Response: Implications for Neural Tube Defects

    DNA damage is associated with hyperhomocysteinemia (HHcy) and neural tube defects (NTDs). Additionally, HHcy is a risk factor for NTDs. Therefore, this study examined whether DNA damage is involved in HHcy-ind...

    Baoling Bai, Chunlei Wan, Zonghui **ao, Dan Li, Lingyun Liu… in Molecular Neurobiology (2024)

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  2. No Access

    Article

    MARK2/Par1b Insufficiency Attenuates DVL Gene Transcription via Histone Deacetylation in Lumbosacral Spina Bifida

    Dishevelled (DVL/Dvl) genes play roles in canonical and noncanonical Wnt signaling, both of which are essential in neural tube closing and are involved in balancing neural progenitor grow...

    Shuyuan Chen, Qin Zhang, Baoling Bai, Shengrong Ouyang, Yihua Bao… in Molecular Neurobiology (2017)