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Article
Efficacy of intratumoral delivery of mitoxantrone in recurrent malignant glial tumours
Ninety-nine patients bearing recurrent malignant glioma sequentially selected according to strict eligibility criteria (72 GBL and 27 AA) entered the study. All patients were previously managed with radiothera...
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Article
Embryonal tumors in the adult population: implications in therapeutic planning
The natural history of neuroectodermal tumors is still debated as far as prognostic factors are concerned; the same uncertainty applies to the optimal radiotherapy schedule and even more to the presumptive ad...
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Article
Progression of motor and cognitive impairment in Parkinson's disease
We performed a longitudinal study (mean follow-up 86.7 months) to evaluate motor and mental deterioration in patients with Parkinson's disease. Of the original 91 patients, only 61 could be re-examined 7 years...
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Article
Platelet heterogeneity based on lactic dehydrogenase activity
Mean lactic dehydrogenase (LDH) activity of human platelets is about 5 nU/platelet; expressed on a cell volume basis, it is 0.5 nU/fl. Platelet separation by means of centrifugation on a Percoll discontinuous ...
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Article
Lactic dehydrogenase activity of platelet subpopulations during pregnancy
We determined the LDH activity of different platelet subpopulations throughout pregnancy. While no changes in LDH content occurred in large, dense platelets, a significant change was found in small, light plat...
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Article
Bone metastasis associated with shunt-related peritoneal deposits from a pineal germinoma
The case of a 15-year-old boy with a pineal germinoma is reported. The patient first underwent a ventriculoperitoneal (VP) shunt followed by a stereotactic biopsy, then, because of the rapidly deteriorating ne...
