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Article
Open AccessDetecting long-range interactions between migrating cells
Chemotaxis enables cells to systematically approach distant targets that emit a diffusible guiding substance. However, the visual observation of an encounter between a cell and a target does not necessarily in...
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Chapter and Conference Paper
Contractile forces during cancer cell invasion
Cell invasion through a dense 3-dimensional matrix is thought to depend on the force balance between the steric hindrance of the matrix on the one hand, and cell traction forces on the other hand. To quantify ...
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Article
Additional inspiratory work of breathing imposed by tracheostomy tubes and non-ideal ventilator properties in critically ill patients
Objective: To determine the tracheostomy tube-related additional work of breathing (WOBadd) in critically ill patients and to show its reduction by different ventilatory modes. Design: P...
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Article
Respiratory comfort of automatic tube compensation and inspiratory pressure support in conscious humans
To compare the new mode of ventilatory Support, which we call automatic tube compensation (ATC), with inspiratory pressure support (IPS) with respect to pereeption of respiratory comfort. ATC unloads the resis...
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Article
Breathing pattern and additional work of breathing in spontaneously breathing patients with different ventilatory demands during inspiratory pressure support and automatic tube compensation
Objective: We designed a new ventilatory mode to support spontaneously breathing, intubated patients and to improve weaning from mechanical ventilation. This mode, named Automatic Tube C...
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Chapter and Conference Paper
New Modes of Ventilatory Support in Spontaneously Breathing Intubated Patients
Controlled mechanical ventilation with/without positive end-expiratory pressure (PEEP) helps in many cases to overcome life-threatening respiratory failure. However, it has some important shortcomings which ma...
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Article
Posters
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Article
Influence of mechanical loading and unloading on respiratory controller gain in healthy subjects
(1) Mechanical unloading (using PAV) increases respiratory controller gain, and mechanical loading decreases it. (2) The observed amplification of periodic breathing under PAV can thus be explained by an incre...
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Article
Respiratory mechanics II
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Article
Acute/Chronic respiratory failure III