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  1. Article

    Open Access

    Comparison of performance of one-color and two-color gene-expression analyses in predicting clinical endpoints of neuroblastoma patients

    Microarray-based prediction of clinical endpoints may be performed using either a one-color approach reflecting mRNA abundance in absolute intensity values or a two-color approach yielding ratios of fluorescen...

    A Oberthuer, D Juraeva, L Li, Y Kahlert, F Westermann… in The Pharmacogenomics Journal (2010)

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    Article

    Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q

    Imbalances in chromosome 11q occur in approximately 30% of primary neuroblastoma and are associated with poor outcome. It has been suggested that 11q loss constitutes a distinct clinico-genetic neuroblastoma s...

    M Fischer, T Bauer, A Oberthür, B Hero, J Theissen, M Ehrich, R Spitz, R Eils… in Oncogene (2010)

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    Article

    Expression of the tumour suppressor gene CADM1 is associated with favourable outcome and inhibits cell survival in neuroblastoma

    Cell adhesion molecule 1 (CADM1) is a putative tumour suppressor gene, which is downregulated in many solid tumours. In neuroblastoma, loss of CADM1 expression has recently been found in disseminated tumours with...

    S Nowacki, M Skowron, A Oberthuer, A Fagin, H Voth, B Brors, F Westermann… in Oncogene (2008)