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Promiscuous G-protein activation by the calcium-sensing receptor
The human calcium-sensing receptor (CaSR) detects fluctuations in the extracellular Ca2+ concentration and maintains Ca2+ homeostasis1,2. It also mediates diverse cellular processes not associated with Ca2+ balan...
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Article
Structure of human GABAB receptor in an inactive state
The human GABAB receptor—a member of the class C family of G-protein-coupled receptors (GPCRs)—mediates inhibitory neurotransmission and has been implicated in epilepsy, pain and addiction1. A unique GPCR that is...
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Article
Author Correction: Structure of human GABAB receptor in an inactive state
An amendment to this paper has been published and can be accessed via a link at the top of the paper.