8 Result(s)
within
Ashfaque A. Memon
Cardiology
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Article
Open AccessMitochondria-DNA copy-number and incident venous thromboembolism among middle-aged women: a population-based cohort study
Venous thromboembolism (VTE) is the third most common cardiovascular disease. Low amount of mitochondrial DNA copy number (mtDNA-CN) has been associated with arterial cardiovascular disease (CVD) and reflects ...
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Article
Open AccessRisk prediction of recurrent venous thromboembolism: a multiple genetic risk model
A single genetic biomarker is unable to accurately predict the risk for venous thromboembolism (VTE) recurrence. We aimed to: (a) develop a multiple single nucleotide polymorphisms (SNPs) model to predict the ...
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Article
Open AccessPolymorphisms in PARK2 and MRPL37 are associated with higher risk of recurrent venous thromboembolism in a sex-specific manner
Recent studies indicate that mitochondrial DNA (mtDNA) dysfunction is a biomarker of oxidative stress and can predict the risk of cardiovascular diseases (CVDs). Genetic variants in PARK2 (rs4708928) and MRPL37 (...
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Article
Open AccessAssociation between TLR9 rs5743836 polymorphism and risk of recurrent venous thromboembolism
Recent gene knockout studies on mice have shown the role of toll-like receptor 9 (TLR9) in resolution of venous thromboembolism (VTE) through sterile inflammation. However, the role of a putative functional TLR9 ...
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Article
Thrombomodulin gene c.1418C>T polymorphism and risk of recurrent venous thromboembolism
Thrombomodulin gene (THBD) is a critical cofactor in protein C anticoagulant system. THBD c.1418C>T polymorphism is reported to be associated with higher risk of primary venous thromboembolism (VTE) but its ro...
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Article
Open AccessPalaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: a randomised cross-over trial
We have previously shown that a Palaeolithic diet consisting of the typical food groups that our ancestors ate during the Palaeolithic era, improves cardiovascular disease risk factors and glucose control comp...
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Article
Open AccessYoga’s effect on inflammatory biomarkers and metabolic risk factors in a high risk population – a controlled trial in primary care
Yoga can reduce blood pressure and has also been suggested to reduce inflammatory biomarkers and metabolic risk factors for cardiovascular diseases (CVDs). We aimed to assess the benefit of two yoga interventi...
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Article
Transforming growth factor (TGF)-β levels and unprovoked recurrent venous thromboembolism
Prediction of recurrence in patients with unprovoked venous thromboembolism (VTE) remains a challenge. Studies of atherosclerosis suggest a protective role of transforming growth factor (TGF)-β. However, the r...
