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  1. Article

    Open Access

    Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

    Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles ha...

    Anne T. Kloek, Mercedes Valls Seron, Ben Schmand in Acta Neuropathologica Communications (2021)

  2. Article

    Open Access

    V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

    Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Here, we have performed a prospect...

    Mercedes Valls Serón, Bart Ferwerda in Acta Neuropathologica Communications (2016)