7 Result(s)

Article

Individual responsiveness of macrophage migration inhibitory factor predicts long-term cognitive impairment after bacterial meningitis

Patients with pneumococcal meningitis are at risk for death and neurological sequelae including cognitive impairment. Functional genetic polymorphisms of macrophage migration inhibitory factor (MIF) alleles ha...

Anne T. Kloek, Mercedes Valls Seron, Ben Schmand… in Acta Neuropathologica Communications (2021)

Article

Complement factor H contributes to mortality in humans and mice with bacterial meningitis

The complement system is a vital component of the inflammatory response occurring during bacterial meningitis. Blocking the complement system was shown to improve the outcome of experimental pneumococcal menin...

E. Soemirien Kasanmoentalib, Mercedes Valls Serón… in Journal of Neuroinflammation (2019)

Article

Erratum to: Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

E. Soemirien Kasanmoentalib, Mercedes Valls Seron… in Journal of Neuroinflammation (2017)

Article

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Disease outcome has been related t...

E. Soemirien Kasanmoentalib, Mercedes Valls Seron… in Journal of Neuroinflammation (2017)

Article

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model

Streptococcus pneumoniae is one of the most important causes of bacterial meningitis, an infection where unfavourable outcome is driven by bacterial and host-derived toxins. In this st...

Kin Ki Jim, JooYeon Engelen-Lee, Astrid M. van der Sar… in Journal of Neuroinflammation (2016)

Article

V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis

Pneumococcal meningitis is the most common and severe form of bacterial meningitis. Fatality rates are substantial, and long-term sequelae develop in about half of survivors. Here, we have performed a prospect...

Mercedes Valls Serón, Bart Ferwerda… in Acta Neuropathologica Communications (2016)