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Article
Raynaud phenomenon: from GWAS to drug repurposing
The identification of novel risk variants in the largest genome-wide association study of Raynaud phenomenon to date provides insights into the pathophysiology of the condition, including the potential role for α
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Article
Skin involvement in early diffuse cutaneous systemic sclerosis: an unmet clinical need
Diffuse cutaneous systemic sclerosis (dcSSc) is associated with high mortality resulting from early internal-organ involvement. Clinicians therefore tend to focus on early diagnosis and treatment of potentiall...
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Article
The pathogenesis, diagnosis and treatment of Raynaud phenomenon
Recent advances in pathogenesis and diagnosis of Raynaud phenomenon have driven, and are driving, new therapeutic strategies for this phenomenon. In this Review, Ariane Herrick provides an update of the pathog...
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Article
A local approach to Raynaud phenomenon
The current treatment options for Raynaud phenomenon are often ineffective and can have undesirable adverse effects. Topical, or transdermal, treatments that increase digital blood flow without systemic advers...