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  1. Article

    Open Access

    An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments

    Metabolic fluxes provide invaluable insight on the integrated response of a cell to environmental stimuli or genetic modifications. Current computational methods for estimating the metabolic fluxes from 13C isoto...

    Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Zamboni… in BMC Bioinformatics (2008)

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  2. No Access

    Chapter and Conference Paper

    A Computational Method for Reconstructing Gapless Metabolic Networks

    We propose a computational method for reconstructing metabolic networks. The method utilizes optimization techniques and graph traversal algorithms to discover a set of biochemical reactions that is most likel...

    Esa Pitkänen, Ari Rantanen, Juho Rousu… in Bioinformatics Research and Development (2008)