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Chapter
Effects of Disruption Circumstances on Contract Renegotiation of Australian PPPs
The COVID-19 pandemic has had a significant and substantial impact on public–private partnership (PPP) projects. The prevention and control measures taken due to the pandemic may lead not only to the governmen...
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Article
Open AccessPatient-Reported Outcomes Through 1 Year of an HIV-1 Clinical Trial Evaluating Long-Acting Cabotegravir and Rilpivirine Administered Every 4 or 8 Weeks (ATLAS-2M)
Advances in HIV-1 therapeutics have led to the development of a range of daily oral treatment regimens, which share similar high efficacy rates. Consequently, more emphasis is being placed upon the individual’...
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Article
Open AccessPatient-Reported Outcomes in ATLAS and FLAIR Participants on Long-Acting Regimens of Cabotegravir and Rilpivirine Over 48 Weeks
The phase 3 ATLAS and FLAIR studies demonstrated that maintenance with Long-Acting (LA) intramuscular cabotegravir and rilpivirine is non-inferior in efficacy to current antiretroviral (CAR) oral therapy. Both...
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Chapter
The Role of Environmental Factors in Promoting and Limiting Biological Invasions in South Africa
South Africa is a megadiverse country in terms of biodiversity, with continental South Africa composed of nine terrestrial biomes. This diversity is in part due to the wide range of climatic and topographic co...
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Chapter
The Global Canopy: Propagating Discipline-Based Global Mobility
As Australian universities welcome significant numbers of inbound international students and increasingly encourage outbound domestic student mobility, the opportunities for global discipline connectedness, cr...
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Article
Open AccessVirologic Effectiveness of Abacavir/Lamivudine with Darunavir/Ritonavir Versus Other Protease Inhibitors in Treatment-Experienced HIV-Infected Patients in Clinical Practice
The standard of care for HIV treatment is a three-drug regimen consisting of two nucleoside reverse transcriptase inhibitors (NRTIs) and either a non-nucleoside reverse transcriptase inhibitor, a protease inhi...
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Article
Open AccessFirst Phase I human clinical trial of a killed whole-HIV-1 vaccine: demonstration of its safety and enhancement of anti-HIV antibody responses
Vaccination with inactivated (killed) whole-virus particles has been used to prevent a wide range of viral diseases. However, for an HIV vaccine this approach has been largely negated due to inherent safety c...
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Article
Open AccessPatient-Reported Symptoms Over 48 Weeks in a Randomized, Open-Label, Phase IIIb Non-Inferiority Trial of Adults with HIV Switching to Co-Formulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir DF versus Continuation of Non-Nucleoside Reverse Transcriptase Inhibitor with Emtricitabine and Tenofovir DF
Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate (EVG/COBI/FTC/TDF; Stribild®) is a guideline-recommended regimen for HIV treatment-naïve patients and a switch option for v...
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Article
Soil infiltrability as a driver of plant cover and species richness in the semi-arid Karoo, South Africa
Data from 199 plots in the semi-arid Karoo showed that relationships between soil infiltrability and plant cover/species richness, as depicted by boundary lines, yielded ecological insights not evident if only...
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Article
Transformation of thicket to savanna reduces soil quality in the Eastern Cape, South Africa
Xeric succulent thicket in the Eastern Cape, South Africa has been used for farming goats since the early 1900s. This habitat is characterised by a dense cover of the succulent bush Portulacaria afra and by a war...
